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To compare the effect of a natural herbal licorice containing preventive measure alternative to chlorohexidine preventive measure to decrease the effect of streptococcus mutans.
A total number of fifty-two patients will be enrolled in the study. They will be divided into two groups: study group and control group. Study group will be subjected to licorice mouthwash and the control will be subjected to chlorohexidine mouth wash. Salivary bacterial count will be evaluated for both groups.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| licorice extract mouthwash | Experimental | administration of a mouthwash containing licorice as a preventive measure to high caries risk patients (faculty of pharmacy, cairo university) |
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| chlorohexidine mouthwash | Placebo Comparator | administration of chlorohexidine 0.2% in 1:1 diluation mouthwash that is broad spectrum antimicrobial activity to high caries risk patients |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| licorice extract mouthwash | Other | mouth rinse that contains a natural herbal licorice root extract used as a preventive measure that reduce caries index. |
|
| Measure | Description | Time Frame |
|---|---|---|
| salivary bacterial count | streotococcus mutans bacterial count | after one week |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| nancy helmy, Msc | Contact | 01002715841 | 002 | nancy.helmy@dentistry.cu.edu.eg |
| sherine hafez, Phd | Contact | 01099296591 | 002 | sherine.hafez@dentistry.cu.edu.eg |
| Name | Affiliation | Role |
|---|---|---|
| nancy helmy, Msc | Faculty of Dentistry, Cairo univerisity | Principal Investigator |
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| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 27129589 | Background | Almaz ME, Sonmez IS, Okte Z, Oba AA. Efficacy of a sugar-free herbal lollipop for reducing salivary Streptococcus mutans levels: a randomized controlled trial. Clin Oral Investig. 2017 Apr;21(3):839-845. doi: 10.1007/s00784-016-1827-y. Epub 2016 Apr 30. | |
| 24021323 | Background | Jain E, Pandey RK, Khanna R. Liquorice root extracts as potent cariostatic agents in pediatric practice. J Indian Soc Pedod Prev Dent. 2013 Jul-Sep;31(3):146-52. doi: 10.4103/0970-4388.117964. |
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| ID | Term |
|---|---|
| D003731 | Dental Caries |
| ID | Term |
|---|---|
| D017001 | Tooth Demineralization |
| D014076 | Tooth Diseases |
| D009057 | Stomatognathic Diseases |
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| chlorohexidine mouthwash | Other | mouth wash that contains chlorohexidine as an active component |
|