Observational Retrospective Study of Evaluation of Prognostic Factors in Advanced Pancreatic Cancer Patients Treated With FOLFIRINOX

Observational Retrospective Study of Evaluation of Prognostic Factors in Advanced Pancreatic Cancer Patients Treated With FOLFIRINOX

The aim of this study is to identify new prognostic factors in patients affected by advanced pancreatic carcinoma treated with first line chemotherapy with FOLFIRINOX regimen. Primary objective is the identification of clinical, laboratory and pathologic factors affecting overall survival of these patients.

Inclusion Criteria:

• age >18 years
• citologically or histologically confirmed pancreatic carcinoma
• disease stage III or IV according to the American Joint Committee on Cancer (AJCC) staging system
• access to clinical informations collected before first-line starting
• availability of objective response evaluation and survival data
• written informed consent

Exclusion Criteria:

• diagnosis of other neoplasia than pancreatic carcinoma
• treatment with drugs other than FOLFIRINOX
• treatment with experimental drugs in combination with FOLFIRINOX
• unavailability of clinical and pathological data