Characterization of the Autofluorescence of Healthy and Pathological Tissues of Vocal Cords

Caractérisation de l'Autofluorescence Des Tissus Sains et Pathologiques Des Cordes Vocales

The aim of this clinical trial is to provide information about autofluorescence of pathological versus healthy vocal folds tissues.

Experimentations are performed on vocal folds biopsies obtained from patients, surgered at ENT department, university hospital of Besançon. After being extracted, samples of vocal folds are submitted to excitations at 365 nm, 405 nm and 450 nm; light spectral absorptions are measured, and results are compared to reference anatomopathology.

Inclusion Criteria:

• patient view in ENT department, presenting vocal fold lesion that necessitate biopsy
• patient informed and with non opposition

Exclusion Criteria:

• small (<1mm) and/or brittle sample
• Patients in emergency situations, pregnant or nursing mothers, persons deprived of their liberty, minors or protected adults.