The Institut has developed a spectrofluorimeter for the registration and monitoring of skin autofluorescence.

This Spectrofluorometer must be initially validated in healthy volunteers. In the long term, it will be used clinically to measure residual photosensitivity of patients who received a photosensitizer in photodynamic therapy.

Inclusion Criteria:

• Man and woman over 18 yers old
• Women of childbearing age under contraceptive
• Healthy volunteers able and willing to follow all procedures of the agreement with the study protocol.
• Healthy volunteers affiliated to the social security
• Ability to provide written informed consent
• Patient's legal capacity to consent to study participation

Exclusion Criteria:

• Healthy volunteers with scars or open wounds on the palms
• Healthy volunteers with warts on their hands
• Healthy volunteers with blister on their hands
• Healthy volunteers involved in another clinical trial
• Pregnant or breastfeeding women
• People in emergencies
• Deprived of liberty or under supervision