Evening Primrose Oil to Misoprostol During Induction of Second-trimester Missed Miscarriage

The Effect of Adding Vaginal Evening Primrose Oil to Misoprostol During Induction of Second-trimester Missed Miscarriage; a Randomized Controlled Trial

Termination of pregnancy is an important subject that has complex and emotional controversies. The most common time of termination of pregnancy is the mid-trimester which has two-thirds of all serious abortion-related complications. There are many indications for mid trimester termination of pregnancy such as missed abortion, serious fetal abnormalities and lastly some women do not wish to continue a pregnancy and will often request termination of pregnancy

Inclusion Criteria:

• Nullipara or previous vaginal delivery only
• Bishop score was ≤ 5
• Women who will accept to participate in the study

Exclusion Criteria:

• Multiple gestations
• Rupture of fetal membranes
• Previous cesarean sections
• Women with heavy bleeding
• Evidence of low implanted placenta by US
• Evidence of intra-uterine infection (either clinical or laboratory)