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The majority of second-trimester pregnancy termination performed in the United States are performed surgically by dilation and evacuation. The frequency of induction of abortion increases as gestational age advances. In the late second trimester and early third trimester, induction is the primary method of termination in cases of fetal abnormalities. In many other countries, however, induction is the primary method of abortion throughout the second trimester
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| extra amniotic misoprostol | Experimental | misoprostol dissolved in warm saline , become dissolute misoprostol saline solution(200 microgram every 4 hours) |
|
| vaginal misoprostol | Experimental | misoprostol tablet soaked with distilled water and inserted in the posterior fornix of the vagina( 200 microgram every 4 hours) |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| termination of second trimester pregnancy | Procedure | Intra uterine extra amniotic (200 μg ) versus Vaginal (200 μg) Misoprostol for Second Trimester Pregnancy Termination. Randomized controlled trial |
| Measure | Description | Time Frame |
|---|---|---|
| mean duration from the initial misoprostol dose until complete fetal expulsion | 24 hours |
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Inclusion Criteria:
Exclusion Criteria:-Pregnancy before 13 weeks.
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| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 34061352 | Derived | Ghosh J, Papadopoulou A, Devall AJ, Jeffery HC, Beeson LE, Do V, Price MJ, Tobias A, Tuncalp O, Lavelanet A, Gulmezoglu AM, Coomarasamy A, Gallos ID. Methods for managing miscarriage: a network meta-analysis. Cochrane Database Syst Rev. 2021 Jun 1;6(6):CD012602. doi: 10.1002/14651858.CD012602.pub2. |
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