CBT4CBT for Office Based Buprenorphine

A Method to Increase Buprenorphine Treatment Capacity

In this Phase II SBIR/STTR project, our Specific Aim will be to determine if the use of CBT4CBT-Buprenorphine leads to clinically significant improved outcomes and increased retention for buprenorphine maintenance patients in a larger and diverse population of individuals seeking buprenorphine treatment in primary care (N=100).

In this phase, 100 individuals entering buprenorphine maintenance at the primary care clinic (Central Medical Unit, CMU) will be randomized to either (1) standard buprenorphine maintenance in which counseling is offered on site, or (2) standard buprenorphine maintenance with CBT4CBT-Buprenorphine substituting for on-site counseling. This will be a 12-week trial.

Inclusion Criteria:

• Meets current Diagnostic Statistical Manual (DSM-5) criteria for opioid use disorder
• Requesting buprenorphine maintenance treatment at Central Medical Unit of the APT Foundation

Exclusion Criteria:

• Unstabilized psychotic disorder
• Currently suicidal or homicidal
• Current cocaine, benzodiazepine, or alcohol use disorder.
• Any history of PCP (phencyclidine) use.
• Pregnant or lactating
• Any other physical or mental condition that would contraindicate office-based buprenorphine maintenance treatment.