Terlipressin Infusion During Whipple Procedure: Effect on Blood Loss and Transfusion Needs

Terlipressin Infusion During Whipple Procedure: Effect on Blood Loss and Transfusion Needs

The present study aims to look at the effect of terlipressin infusion on blood loss and blood transfusion needs during Whipple procedure

Inclusion Criteria:

• All patients older than 18 years of age,
• ASA classification class I and II,
• Patients assigned for Whipple procedure.

Exclusion Criteria:

• Preoperative renal failure,
• Severe liver dysfunction (Child-Turcotte-Pugh grade C),
• Hyponatremia (Na+ <132mmol/l),
• Severe valvular heart disease,
• Heart failure,
• Symptomatic coronary heart disease,
• Bradycardic arrhythmia (heart rate < 60/min),
• Peripheral artery occlusive disease (clinical stadium II-IV),
• Uncontrolled arterial hypertension (Blood pressure >160/100mmHg despite intensive treatment),
• Pregnancy.