Effect of Terlipressin Infusion on Systemic and Hepatic Hemodynamics During Hepatobiliary Surgery

Effect of Terlipressin Infusion on Systemic and Hepatic Hemodynamics During Hepatobiliary Surgery

To evaluate the effect of terlipressin infusion on systemic and hepatic hemodynamics during hepatobiliary surgery

Inclusion Criteria:

• Age > 18 years.
• Any gender.
• ASA (American Society of Anesthesiologists) Classification( Class I-II)
• Patients undergoing major elective hepatobiliary surgery.

Exclusion Criteria:

• Preoperative renal failure (GFR < 50 ml/min).
• Severe liver dysfunction (Child- turcotte -Pugh grade C).
• Hyponatremia (<132 mmol/l).
• Severe aortic regurgitation, severe mitral regurgitation, heart failure.
• Symptomatic coronary heart disease.
• Bradycardic arrhythmia (heart rate < 60/min).
• Peripheral artery occlusive disease (clinical stadium II-IV).
• Uncontrolled arterial hypertension (Blood pressure >160/100 mmHg despite intensive treatment).
• Pregnancy.