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By showing that increased levels of acidotic metabolites and electrolytes in the systemic blood of patients who do not receive portal blood flush prior to reperfusion compared to patients who do receive portal blood flush, and that these increased levels correlate with cardiac depression as seen on TEE, the investigators hope to find a superior technique for liver reperfusion.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Portal Blood Flush | participants that receive the portal blood flush | ||
| No Portal Blood Flush | participants that don't receive the portal blood flush |
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| Measure | Description | Time Frame |
|---|---|---|
| Hemodynamic Stability | The primary objective of this study is to determine whether or not a portal blood flush is useful for maintaining hemodynamic stability in the peri-reperfusion stage of Orthotopic Liver Transplantation as evidence by TEE. | 5 days |
| Measure | Description | Time Frame |
|---|---|---|
| correlation between the cardiac dysfunction and the degree of hyperkalemia seen after reperfusion. | The secondary objective is to determine if there is a correlation between cardiac dysfunction as measured by a qualitative analysis of TEE and the degree of hyperkalemia measured by a post reperfusion blood sample. | 5 days |
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Inclusion Criteria:
Exclusion Criteria:
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Liver Transplant
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| Name | Affiliation | Role |
|---|---|---|
| Grayce Davis, MD | Medical University of South Carolina | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Medical University of South Carolina | Charleston | South Carolina | 29425 | United States |
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| ID | Term |
|---|---|
| D008107 | Liver Diseases |
| ID | Term |
|---|---|
| D004066 | Digestive System Diseases |
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