Study to Evaluate Performance of the Organ Recovery Systems LifePort® Liver Transporter System, a Machine Perfusion System, for Liver Transplant

A Prospective Randomized Multi-Center Study of the Use of the Organ Recovery Systems LifePort® Liver Transporter (LLT) System With Vasosol® as Compared to Static Cold Storage in Orthotopic Liver Transplants (Perfusion to Improve Liver Outcomes in Transplantation)

Comparison of hypothermic machine perfusion of livers to standard of care (static cold storage).

Prospective, randomized, multi-center study to show safe and effective use of whole liver preservation via hypothermic machine perfusion (HMP) as compared to livers preserved by static cold storage.

Inclusion Criteria:

• ≥18 years of age
• Active on the United Network for Organ Sharing (UNOS) waiting list for liver transplantation
• De novo liver transplant recipient
• Written informed consent required

Exclusion Criteria:

• Subject is a multi-organ transplant recipient
• Subject is antibodies blood group (ABO) liver incompatible
• Subject has severe systemic infection
• Subject is Human Immunodeficiency Virus (HIV) positive
• Subject has acute/fulminant liver failure
• Subject is pregnant