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| Name | Class |
|---|---|
| Institute for Neurosciences of Montpellier U1051 | UNKNOWN |
| Reims University hospital | OTHER |
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To date, all the electrophysiological methods for auditory testing rely on the measure on synchronous evoked auditory nerve activity. This measure only takes into account the response of the first action potential in every auditory fibber, but provides no information about the neural response during a sustained activity. This can explain why in experimental models, a loss of more of 80% of auditory nerve fibbers cannot be detected by usual electrophysiological measurements. In this study we aim at investigating the global spontaneous and sound evoked auditory nerve activity by recording directly the electrical field by an electrode placed directly on the auditory nerve of subjects during a skull base surgical procedure. We expected to demonstrated differences in the electrical activity between subjects with or without hearing loss.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Subjects with no hearing loss | Experimental | Subjects referred for cerebellopontine angle surgery with no hearing loss with recording of auditory nerve activity by contact electrode |
|
| Subjects with hearing loss | Experimental | Subjects referred for cerebellopontine angle surgery with hearing loss with recording of auditory nerve activity by contact electrode |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Recording of auditory nerve activity | Procedure | near field recording of auditory nerve activity with contact electrode |
|
| Measure | Description | Time Frame |
|---|---|---|
| Amplitude of global evoked auditory nerve activity | 36 months | |
| Spectrum of global evoked auditory nerve activity | 36 months |
| Measure | Description | Time Frame |
|---|---|---|
| Mesure of peristimulus time responses of evoked auditory nerve activity | 36 months |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Frédéric VENAIL, PU-PH | University Hospital, Montpellier | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| CHU Montpellier | Montpellier | 34295 | France |
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| ID | Term |
|---|---|
| D034381 | Hearing Loss |
| D014012 | Tinnitus |
| ID | Term |
|---|---|
| D006311 | Hearing Disorders |
| D004427 | Ear Diseases |
| D010038 | Otorhinolaryngologic Diseases |
| D012678 | Sensation Disorders |
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| D009461 |
| Neurologic Manifestations |
| D009422 | Nervous System Diseases |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |