Analgesic Efficacy of Duloxetine in Patients Undergoing Lumbar Discectomy

Analgesic Efficacy of Duloxetine in Patients Undergoing Lumbar Discectomy: Randomized Trial

Duloxetine is a serotonin-norepinephrine reuptake inhibitor primarily used for treatment of major depression and anxiety. Duloxetine also has been used in the treatment of chronic pain conditions, such as osteoarthritis and musculoskeletal pain. There are few studies examining its effect for acute pain. The objective of this study is to evaluate the analgesic effect of duloxetine for patients undergoing lumbar discectomy.

Inclusion Criteria:

• Patients undergoing lumbar discectomy

Exclusion Criteria:

• Patients on regular opioid therapy
• Uncontrolled hypertensive patients
• Patients with ischemic heart disease