Determining Whether Multiple Anesthesia Exposures Affect Cognitive Function for Retinoblastoma Patients

Incidence of Neurocognitive Deficits in Patients After Treatment for Retinoblastoma With Multiple Anesthesia Exposures

The purpose of this study is to see if there is a difference between the development of the brain (neurodevelopment) in children who have been treated for retinoblastoma with multiple anesthetic exposures, compared with brain development in children who have never had anesthesia.

Inclusion Criteria:

• Age ≥ 6 and < 17 years old

Exclusion Criteria:

• Diagnosis of any secondary disease associated with developmental delay
• History of second cancer diagnosis
• Legal Blindness
• Past surgery of any type, with the exception of enucleation for retinoblastoma
• Past exposure to anesthesia for surgical intervention
• More than one anesthesia encounter for surgical intervention before diagnosis at MSK
• Past External Beam Radiation for treatment of retinoblastoma
• Past systemic chemotherapy
• Non-native speaker of English; however, children whose parents speak only Spanish will be included, because the tests for parents are available in Spanish