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The study aims to determine whether there is a need for preparative fasting prior to contrast-enhanced computed tomography (CT).
The use of fasting orders for imaging and other procedures is common, this seemingly benign practice can lead to real harms to patients and poor satisfaction with their care. The nothing per os (NPO) order is sometimes used in CT scans because gastrointestinal tract contents can interrupt visualization of the intestinal lumen, but more commonly NPO orders are are thought to protect all supine patients from aspiration during delivery of intravenous contrast. There is limited evidence to support such practice of NPO orders prior to contrast-enhanced CT scans. The authors' main objective is to determine if there is a need for preparative fasting prior to contrast-enhanced CT scans.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Fasting arm | Patients will need at least 4 hours of fasting prior to contrast-enhanced CT scans. | ||
| No fasting | Patients are allowed to eat and drink freely prior to contrast-enhanced CT scans. |
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| Measure | Description | Time Frame |
|---|---|---|
| Aspiration pneumonitis | Rates of aspiration pneumonitis after contrast-enhanced CT scans | Day 1 |
| Measure | Description | Time Frame |
|---|---|---|
| Gastrointestinal symptoms | Rates of nausea and vomiting after contrast-enhanced CT scans | Hour 1 |
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Inclusion Criteria:
- Patients undergoing contrast-enhanced CT scans
Exclusion Criteria:
Pateints undergoing CT scans while sedated.
Patients under the age of 18 years
Patients who suffer from a mental disorder that prevents them:
Patients who were instructed not to eat due to requirements of a specific study (for example.. computed tomography enterography-CTE)
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The participants are inpatients who are undergoing contrast enhanced computed tomography that will be divided into two cohorts. The first will need at least 4 hours of fasting prior to contrast enhanced computed tomography scans and the second will be allowed to eat and drink freely prior to contrast enhanced computed tomography scans
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| Name | Affiliation | Role |
|---|---|---|
| Naiel Bisharat, MD | Emek Medical Center | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Emek Medical Center | Afula | 18341 | Israel |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 32901302 | Derived | Neeman Z, Abu Ata M, Touma E, Saliba W, Barnett-Griness O, Gralnek IM, Rock W, Bisharat N. Is fasting still necessary prior to contrast-enhanced computed tomography? A randomized clinical study. Eur Radiol. 2021 Mar;31(3):1451-1459. doi: 10.1007/s00330-020-07255-0. Epub 2020 Sep 8. |
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