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To compare the performance of different negative oral contrast agents in bowel distension in patient referred for PET/CT studies for various causes aiming for identification of ideal oral contrast agent(OCA).
Evaluation of gastrointestinal pathology depends on adequate bowel distention, which optimizes resolution of the bowel wall and contents. Traditionally, high-attenuation oral Contrast material in the form of iodine solutions or barium suspensions has been used to obtain bowel distension in MDCT examinations
Traditional high-contrast oral agents like iodine solutions, and barium suspensions which due to overcorrection problems in PET-CT interpretation lowers the accuracy of diagnosis. Negative oral contrast agents like water, air, fat containing agents used with 12.5% corn oil and polyethylene glycol has been used in radiological studies. Milk with 4% fat content has also been tested out in radiological studies and found to be effective. As it is more easily available, palatable, and acceptable especially, by children it needed to be tested in the visualization of the GIT in the PET-CT studies compared to other negative contrast agents.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Water | Patients who ingested only water as an oral contrast |
| |
| Milk | Patients who ingested milk as an oral contrast |
| |
| Mannitol | Patients who ingested mannitol as an oral contrast |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| oral contrast | Other | negative oral contrast utilization in PET/CT studies |
|
| Measure | Description | Time Frame |
|---|---|---|
| compare the performance of different negative oral contrast agents in PET/Ct studies | comparing the effect of different oral contrast on bowel distention | baseline |
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Inclusion Criteria:
Exclusion Criteria:
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Consecutive patients in our institution who prepared for PET-CT with administration of oral contrast material
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Nahla mostafa Bashank, Phd | Contact | 01009466255 | nahla_bashank_2006@yahoo.com |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Faculty of Medicine | Recruiting | Asyut | 71515 | Egypt |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 23919067 | Background | Meyer SA, Gawde S. Utility of negative oral contrast (milk with 4% fat) in PET-CT studies. Indian J Nucl Med. 2012 Jul;27(3):151-5. doi: 10.4103/0972-3919.112719. | |
| 18430848 | Background | Koo CW, Shah-Patel LR, Baer JW, Frager DH. Cost-effectiveness and patient tolerance of low-attenuation oral contrast material: milk versus VoLumen. AJR Am J Roentgenol. 2008 May;190(5):1307-13. doi: 10.2214/AJR.07.3193. |
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| ID | Term |
|---|---|
| D003287 | Contrast Media |
| ID | Term |
|---|---|
| D064907 | Diagnostic Uses of Chemicals |
| D020228 | Pharmacologic Actions |
| D020164 | Chemical Actions and Uses |
| D020313 | Specialty Uses of Chemicals |
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