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Intraoperative hypotension occurs often and is associated with adverse patient outcomes such as stroke, myocardial infarction and renal injury.
The aim of this study was to test the accuracy of a physiology-based machine-learning algorithm using continuous non-invasive measurement of the blood pressure waveform with the Nexfin® finger cuff during surgery.
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Hypotension Probability Indicator | Diagnostic Test | The accurary of the Hypotension Probability Indicator (HPI) is tested in the created offline database. This means data was prospectively collected but the HPI algorithm was not tested prospectively but after collection in the offline database. |
| Measure | Description | Time Frame |
|---|---|---|
| Sensitivity of the HPI algorithm | Sensitivity | three minutes prior to the hypotensive event |
| Specifity of the HPI algorithm | Specifity | three minutes prior to the hypotensive event |
| Measure | Description | Time Frame |
|---|---|---|
| Predictive positive value of the HPI algorithm | Predictive positive value | one minute prior to the hypotensive event |
| Predictive positive value of the HPI algorithm | Predictive positive value |
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Inclusion Criteria:
Exclusion Criteria:
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All adult patients undergoing surgery in the AMC were included in the study. Subjects were only excluded when technical problems or strong local vasoconstriction (i.e., cold fingers) prevented the Nexfin® non-invasive blood pressure finger cuff measurement. Subjects were not excluded for any other reason besides technical failure.
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 33927105 | Derived | Wijnberge M, van der Ster BJP, Geerts BF, de Beer F, Beurskens C, Emal D, Hollmann MW, Vlaar APJ, Veelo DP. Clinical performance of a machine-learning algorithm to predict intra-operative hypotension with noninvasive arterial pressure waveforms: A cohort study. Eur J Anaesthesiol. 2021 Jun 1;38(6):609-615. doi: 10.1097/EJA.0000000000001521. |
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| two minutes prior to the hypotensive event |
| Predictive positive value of the HPI algorithm | Predictive positive value | three minutes prior to the hypotensive event |
| Predictive positive value of the HPI algorithm | Predictive positive value | four minutes prior to the hypotensive event |
| Predictive positive value of the HPI algorithm | Predictive positive value | five minutes prior to the hypotensive event |
| Predictive positive value of the HPI algorithm | Predictive positive value | ten minutes prior to the hypotensive event |
| Predictive positive value of the HPI algorithm | Predictive positive value | 15 minutes prior to the hypotensive event |
| Negative predictive value of the HPI algorithm | Negative predictive value | one minute prior to the hypotensive event |
| Negative predictive value of the HPI algorithm | Negative predictive value | two minutes prior to the hypotensive event |
| Negative predictive value of the HPI algorithm | Negative predictive value | four minutes prior to the hypotensive event |
| Negative predictive value of the HPI algorithm | Negative predictive value | five minutes prior to the hypotensive event |
| Negative predictive value of the HPI algorithm | Negative predictive value | ten minutes prior to the hypotensive event |
| Negative predictive value of the HPI algorithm | Negative predictive value | 15 minutes prior to the hypotensive event |
| Time from HPI alarm to hypotensive event during surgery | Time from HPI alarm to hypotensive event, this can range from 0,1 min to a high number such as 30 or even 40 minutes. | From the onset of the HPI alarm to the hypotensive event during surgery, this is in minutes. (this can range from 0,1 min to a high number such as 30 or even 40 minutes) |
| Sensitivity of the HPI algorithm | Sensitivity | one minute prior to the hypotensive event |
| Sensitivity of the HPI algorithm | Sensitivity | two minutes prior to the hypotensive event |
| Sensitivity of the HPI algorithm | Sensitivity | five minutes prior to the hypotensive event |
| Sensitivity of the HPI algorithm | Sensitivity | ten minutes prior to the hypotensive event |
| Sensitivity of the HPI algorithm | Sensitivity | 15 minutes prior to the hypotensive event |
| Specifity of the HPI algorithm | Specifity | one minute prior to the hypotensive event |
| Specifity of the HPI algorithm | Specifity | two minutes prior to the hypotensive event |
| Specifity of the HPI algorithm | Specifity | five minutes prior to the hypotensive event |
| Specifity of the HPI algorithm | Specifity | ten minutes prior to the hypotensive event |
| Specifity of the HPI algorithm | Specifity | 15 minutes prior to the hypotensive event |