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PACU-HPI study evaluates the use of a hemodynamic monitor in the post-anesthetic recovery room on patients undergoing colorectal, hepatobiliary, and vascular surgery, to determine the feasibility of recruiting this surgical population.
Postoperative vascular complications, including myocardial infarction (MI), myocardial injury after noncardiac surgery (MINS), stroke, and death occur in up to 18% of surgical patients.1 Hypotension is a frequent occurrence in the postoperative period and can increase the risk of postoperative vascular complications.2 Therefore, accurate prediction of postoperative hypotension can identify patients at risk for postoperative vascular complications who would benefit from early intervention. The investigators propose a feasibility study to determine the accuracy of the hypotension prediction index (HPI) parameter of the HemoSphere monitor and Acumen IQ sensor (Edwards Lifesciences, Irvine, CA) to predict postoperative hypotension in surgical patients.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| HPI monitor |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Device: HemoSphere monitor and Acumen IQ sensor. | Device | Patients will be placed on this monitor for the duration of study in the PACU. Followed by 30-day phone call to record cardiovascular complications. |
| Measure | Description | Time Frame |
|---|---|---|
| Incidence of intraoperative hypotension | Describe the incidence of hypotension defined as MAP <65 intraoperatively. | in 12 months |
| Incidence of postoperative hypotension | Describe the incidence of postoperative hypotension defined as MAP <65 in the PACU | in 12 months |
| Hemodynamic changes with treatment of hypotension | Described the changes in cardiac index with each medical treatment of a hypotensive episode. | in 12 months |
| Measure | Description | Time Frame |
|---|---|---|
| Sensitivity and Specificity of HPI | Sensitivity and Specificity of HPI compared to a hypotensive events in the postoperative setting | in 12 months |
| Cardiovascular outcomes | Number of patients with Mortality, MI, MINS, acute pulmonary edema, stroke, pulmonary embolism, deep vein thrombosis |
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Inclusion Criteria:
Exclusion Criteria:
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Surgical patients with cardiovascular disease risk factors undergoing colorectal, hepatobiliary, or vascular surgery.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Stephen Yang, MD, MSc | Contact | (514) 340-8222 | stephen.yang@mail.mcgill.ca | |
| Mirana Rakotoarivony | Contact | mirana.rakotoarivony@affiliate.mcgill.ca |
| Name | Affiliation | Role |
|---|---|---|
| Stephen Yang, MD, MSc | Jewish General Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Jewish General Hospital, Anesthesia Department | Recruiting | Montreal | Quebec | H3S 1Y9 | Canada |
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| in 12 months |