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| Name | Class |
|---|---|
| Massachusetts General Hospital | OTHER |
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Tourette Syndrome (TS) and Persistent Tic Disorder (PTD) are chronic and potentially disabling neurobiological conditions. Although a range of pharmacological and psychosocial treatments exists, a significant number of individuals either do not respond to the current treatments, find them unacceptable, or cannot access them. Thus, it is essential that researchers continue to pursue novel treatment approaches that can also be easily disseminated to those in need.
Initial pilot data suggest that a mindfulness-based intervention may be beneficial for adults with tic disorders. In the present study, the researchers aim to further develop this mindfulness-based intervention, adapt it to be delivered online and pilot test the intervention with a small group of participants. The data from this pilot test will inform a subsequent randomized controlled trial comparing online mindfulness-based tic reduction to online psychoeducation, relaxation, and supportive therapy.
The specific aim is to determine the feasibility and acceptability of Online Mindfulness-based Tic Reduction in 6 adults with TS or PTD.
The researchers hypothesize that Online Mindfulness-based Tic Reduction will be feasible and acceptable to adults with tic disorders as measured by participant satisfaction, qualitative participant feedback, home practice compliance, dropout, and adverse events.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Online Mindfulness-based Tic Reduction | Experimental |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Online Mindfulness-based Tic Reduction | Behavioral | 8-week online group mindfulness-based intervention for tics |
|
| Measure | Description | Time Frame |
|---|---|---|
| Patient Satisfaction Questionnaire | week 9 |
| Measure | Description | Time Frame |
|---|---|---|
| Homework Compliance Questionnaire | Weeks 1-8 | |
| Attrition Form | Weeks 1-8 | |
| Adverse Events Monitoring Form |
| Measure | Description | Time Frame |
|---|---|---|
| Yale-Brown Obsessive Compulsive Scale | Week 0, Week 9 | |
| Attention Deficit Hyperactivity Disorder Rating Scale | Week 0, Week 9 | |
| Patient Health Questionnaire-9 |
Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Hannah Reese, Ph.D. | Bowdoin College | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Bowdoin College | Brunswick | Maine | 04011 | United States | ||
| Massachusetts General Hospital |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 33757602 | Derived | Reese HE, Brown WA, Summers BJ, Shin J, Wheeler G, Wilhelm S. Feasibility and acceptability of an online mindfulness-based group intervention for adults with tic disorders. Pilot Feasibility Stud. 2021 Mar 24;7(1):82. doi: 10.1186/s40814-021-00818-y. |
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| ID | Term |
|---|---|
| D005879 | Tourette Syndrome |
| D013981 | Tic Disorders |
| ID | Term |
|---|---|
| D001480 | Basal Ganglia Diseases |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
| D009422 | Nervous System Diseases |
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| Weeks 1-9 |
| Yale Global Tic Severity Scale (YGTSS) | Week 0, Week 9 |
| Adult Tic Questionnaire | Weeks 0-9 |
| Clinical Global Impressions Scale-Severity | Week 0, Week 9 |
| Clinical Global Impressions Scale-Improvement | Week 9 |
| Week 0, Week 9 |
| Work and Social Adjustment Survey | Week 0, Week 9 |
| Five Facet Mindfulness Questionnaire | Weeks 0-9 |
| Credibility and Expectancy Questionnaire | Week 3 |
| Self Compassion Scale | Week 0, Week 9 |
| Affective Reactivity Index | Week 0, Week 9 |
| Brief Irritability Test | Week 0, Week 9 |
| Boston |
| Massachusetts |
| 02114 |
| United States |
| D009069 | Movement Disorders |
| D020271 | Heredodegenerative Disorders, Nervous System |
| D019636 | Neurodegenerative Diseases |
| D030342 | Genetic Diseases, Inborn |
| D009358 | Congenital, Hereditary, and Neonatal Diseases and Abnormalities |
| D065886 | Neurodevelopmental Disorders |
| D001523 | Mental Disorders |