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This prospective interventional study investigates transpharyngeal sonography (TPS) as an additional neuromonitoring strategy to assess cerebral perfusion during cardiovascular surgery. In the first part of the study the investigators will investigate the feasibility of TPS for visualization of aortic arch branches including the innominate and the carotid arteries in patients undergoing cardiac surgery with cardiopulmonary bypass. In the second part the investigators plan to adopt the investigators previous experiences on TPS to a selected population of patients undergoing ascending aortic and/or arch repair in hypothermic circulatory arrest (HCA).
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| 20 patients (1-20) validation arm | Experimental | Accuracy of cerebral flow measurement between TPS and CDS in 20 patients undergoing cardiovascular surgery with cardiopulmonary bypass |
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| 20 patients (21-40) HCA arm | Experimental | Assessment and comparison of TPS and CDS in hypothermic circulatory arrest (HCA) during cardiovascular surgery |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Transpharyngeal Doppler sonography (TPS) | Diagnostic Test | Usage of transpharyngeal Doppler to assess cerebral perfusion during cardiovascular surgery |
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| Measure | Description | Time Frame |
|---|---|---|
| Accuracy of cerebral flow velocity measurement | Cerebral blood flow velocity measurements will be performed with transpharyngeal Doppler sonography (TPS) and conventional colour-coded Duplex sonography (CDS). Doppler flow velocities (obtained at the same intraoperative phase and at the same time) will be compared between TPS and CDS TPS and different Doppler techniques. | intraoperative phase, expected to be ca. 4 hours |
| Measure | Description | Time Frame |
|---|---|---|
| Hypothermic Circulatory Arrest | Doppler flow velocities (obtained with both methods in the Phase of hypothermic circulatory arrest - intraoperatively) will be compared between TPS and CDS TPS and different Doppler techniques. | intraoperative phase, expected to be ca. 4 hours |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Inselspital, University Hospital Bern, University of Bern | Bern | 3010 | Switzerland |
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| Conventional colour-coded Duplex sonography (CDS) | Diagnostic Test | Usage of conventional colour-coded Duplex sonography (CDS) to assess cerebral perfusion during cardiovascular surgery |
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