RSA Study of Persona TKA With CR vs MC Polyethylene

Aspects of Alignment, Function, and Migration Behaviour in Two Conceptually Different Articular Surface Designs in the Cruciate Retaining Version of the Cemented Persona Knee System - A Randomized Study Evaluated by RSA and CT Analysis

The aim of this study is to evaluate, over a 2 year period, the migration pattern, function and the possibility of anatomical reconstruction of a relatively new total knee arthroplasty (TKA) concept, the Persona. Sixty patients will be randomized into 2 groups of 30 patients each, with one group receiving the Persona TKA with a conventional Cruciate Retaining (CR) polyethylene articular surface and the other group with a newly developed Medial Congruent (MC) articular surface. Patients will be followed up with Radiostereometry (RSA), conventional radiography, outcome questionnaires, clinical evaluation and Computer Tomography (CT). The migration pattern of the components will be evaluated as well as the degree of anatomical reconstruction and clinical result.

We plan also to do a 5 year follow-up of the patients with RSA and PROMS.

Inclusion Criteria:

• Osteoarthritis of the knee necessitating knee replacement
• ASA I-III
• BMI 18 - 35

Exclusion Criteria:

• Joint sepsis in history
• immunosuppresive drugs last 5 years
• Rheumatoid arthritis
• Severe osteoporosis or other metabolic bone diseases
• Neuromuscular diseases
• Personal disorders suspected of limiting rehab and completion of the trial period
• Previous osteotomy of affected limb
• Intra-articular knee fracture of affected limb
• Peroperative fracture
• Severe deformity of affected joint in need of augmentation or excessive release
• Obvious need for more constrained knee than CR