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| Name | Class |
|---|---|
| Castilla-León Health Service | OTHER |
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This is a randomized clinical trial aimed at postmenopausal women aged 50 to 64 years old selected in urban primary care centers of two centers (Spain). Its objective is to evaluate the effects of the additional intake of high cocoa content chocolate on blood pressure, vascular function, body composition, quality of life and cognitive performance.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Control group | No Intervention | No intervention | |
| Intervention group | Experimental | Addition of 10 g/day of high cocoa content chocolate to the usual diet for six months |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Intervention group | Dietary Supplement | 10 g/day of high cocoa content chocolate for six months. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Blood pressure | Measurement by oscillometric method (mmHg) | 6 months |
| Measure | Description | Time Frame |
|---|---|---|
| Arterial stiffness | Measurement by Brachial-ankle pulse wave velocity (m/s) | 6 months |
| Wave reflection | Measurement by central and peripheral augmentation index |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Jose I Recio-Rodriguez, PhD | University of Salamanca | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Instituto Biosanitario de Salamanca. Research unit La Alamedilla | Salamanca | 37003 | Spain |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 33190575 | Derived | Garcia-Yu IA, Garcia-Ortiz L, Gomez-Marcos MA, Rodriguez-Sanchez E, Mora-Simon S, Maderuelo-Fernandez JA, Recio-Rodriguez JI. Effects of cocoa-rich chocolate on cognitive performance in postmenopausal women. A randomised clinical trial. Nutr Neurosci. 2022 Jun;25(6):1147-1158. doi: 10.1080/1028415X.2020.1840119. Epub 2020 Nov 15. | |
| 30552275 |
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| 6 months |
| Body composition | Measurement by body fat percentage | 6 months |
| Quality of life | Measurement by Cervantes Scale (Score between 0 (poor quality) and 155 (high quality) | 6 months |
| Cognitive performance | Measurement by executive function | 6 months |
| Garcia-Yu IA, Garcia-Ortiz L, Gomez-Marcos MA, Alonso-Dominguez R, Gonzalez-Sanchez J, Mora-Simon S, Gonzalez-Manzano S, Rodriguez-Sanchez E, Maderuelo-Fernandez JA, Recio-Rodriguez JI. Vascular and cognitive effects of cocoa-rich chocolate in postmenopausal women: a study protocol for a randomised clinical trial. BMJ Open. 2018 Dec 14;8(12):e024095. doi: 10.1136/bmjopen-2018-024095. |