Effect of Cocoa Consumption in Cardiovascular and Immune Parameters

Randomized Clinical Trial of the Effect of Cocoa Consumption in Cardiovascular and Immune Parameters in Colombian Patients With Newly Diagnosed Stage 1 Arterial Hypertension

Arterial hypertension is one of the most preventable risk factors for stroke, cardiovascular and renal disease. Cocoa is rich in a subclass of flavonoid called flavanol this increase nitric oxide production and is involved in controlling blood pressure.

Inclusion Criteria:

• Age: 18 - 65 years old
• Resides in Medellín City
• Attached from the contributive regimen of Colombian Health System
• Essential Arterial Hypertension, stage I. Diagnosis less than 3 months.
• Medically indicated non-pharmacological therapy.
• Voluntary desire to consume 50 grams of chocolate per day for 12 weeks.
• Voluntary desire to participate in the trial and sign informed consent.

Exclusion Criteria:

• Suspect of secondary hypertension
• Suspect of injury in target organ
• Presence of diabetes mellitus
• BMI (Body Mass Index) major or equal to 30
• Present smoker or with less than four weeks of abstinence of tobacco
• Consume antiplatelet substances
• Regular consumption of antioxidants, multivitamins, anti-inflammatory medications, drugs for nasal congestion and sibutramine