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Psoriasis is a common autoimmune disease. It affects women of all ages including reproductive years. Autoimmune diseases including psoriasis are linked to premature ovarian reserve. This study aims to measure serum hormones including FSH,LH,E2,PRL and AMH (indicators of ovarian reserve) in women with and without psoriasis.
Psoriasis is a common autoimmune disease. It affects women of all ages including reproductive years. Almost 75% of patients are diagnosed before the age of 40. There is also increased evidence on autoimmune disease and their link to premature ovarian failure.Ovarian reserve is important for the reproductive period. The measurements of serum hormones including follicle stimulating hormone (FSH),luteinizing hormone (LH),prolactin (PRL), estradiol (E2) and anti-mullerian hormone (AMH) will give us an idea about the ovarian reserve. The investigators aim is to measure ovarian reserve parameters in patients newly diagnosed with psoriasis and to compare them to healthy controls. Serum FSH,LH,E2,PRL and AMH will be measured on the 3rd day of the cycle.The serum hormone levels will be compared between women with psoriasis and women without psoriasis
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Women with Psoriasis | Reproductive age women newly diagnosed with psoriasis |
| |
| Women without Psoriasis | Reproductive age women without psoriasis to serve as control |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Hormone panel | Other | Blood sampling on the 3rd day of menstrual cycle for the measurement of serum FSH,LH,PRL,E2 and AMH hormone levels. |
|
| Measure | Description | Time Frame |
|---|---|---|
| to compare serum AMH levels between the two groups | Serum AMH levels will be measured (using ELISA) and compared between the two groups | 1 day |
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Inclusion Criteria:
Exclusion Criteria:
Female
The study population will be reproductive age women diagnosed with psoriasis. The control population will be aged and BMI matched women without psoriasis.
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| Name | Affiliation | Role |
|---|---|---|
| Berna Aslan Cetin, MD | Kanuni Sultan Suleyman Research and Training Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Kanuni Sultan Suleyman Research and Training Hospital | Istanbul | 34303 | Turkey (Türkiye) |
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| Label | URL |
|---|---|
| premature ovarian failure in patients with psoriasis | View source |
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| ID | Term |
|---|---|
| D011565 | Psoriasis |
| ID | Term |
|---|---|
| D017444 | Skin Diseases, Papulosquamous |
| D012871 | Skin Diseases |
| D017437 | Skin and Connective Tissue Diseases |
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Blood samples for the measurement of serum FSH,LH,E2,PRL and AMH