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This study investigates how alcohol affects the immune system and behavior in healthy adults. The study also will examine how an individual's typical drinking habits may affect the immune system's response to alcohol.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Alcohol, placebo | Experimental | Alcohol, ethyl - Placebo |
|
| Alcohol, low dose | Experimental | Alcohol, ethyl - Low dose |
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| Alcohol, moderate dose | Experimental | Alcohol, ethyl - Moderate dose |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Alcohol, Ethyl | Drug | Randomized within-subjects design |
|
| Measure | Description | Time Frame |
|---|---|---|
| Plasma lipopolysaccharide (pg/ml) | Plasma concentration of lipopolysaccharide, measured in picograms/ml | 0-4 hours |
| Plasma lipopolysaccharide binding protein (ng/ml) | Plasma concentration of lipopolysaccharide binding protein, measured in nanograms/ml | 0-4 hours |
| Soluble cluster of differentiation 14 (ng/ml) | Plasma concentration of soluble cluster of differentiation 14, measured in nanograms/ml | 0-4 hours |
| Soluble cluster of differentiation 163 (ng/ml) | Plasma concentration of soluble cluster of differentiation 163, measured in nanograms/ml | 0-4 hours |
| Measure | Description | Time Frame |
|---|---|---|
| Response time in ms | Response time in milliseconds, as measured by the NIH Toolbox and Cued Go/No-Go test | 0-4 hours |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Brown University | Providence | Rhode Island | 02912 | United States |
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| ID | Term |
|---|---|
| D000428 | Alcohol Drinking |
| ID | Term |
|---|---|
| D004327 | Drinking Behavior |
| D001519 | Behavior |
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| ID | Term |
|---|---|
| D000431 | Ethanol |
| ID | Term |
|---|---|
| D000438 | Alcohols |
| D009930 | Organic Chemicals |
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| Alcohol, Ethyl - placebo | Other | Randomized within-subjects design |
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