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| Name | Class |
|---|---|
| Duquesne University | OTHER |
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The project goal is to identify if herbal teas consumed three times per day over a period of three months can improve these markers of bone health as well as improve quality of life (QOL) compared to women taking placebo by increasing osteoblast activity, decreasing osteoclast activity, increasing nocturnal melatonin levels and by decreasing C-reactive protein (CRP) and cortisol levels. Our central hypothesis is that these herbal teas will improve both objective and subjective measures of bone health in a population with osteopenia not taking this regimen by reducing osteoclast activity and increasing osteoblast activity and by reducing stress and anxiety.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Herbal Tea 1 | Placebo Comparator | Placebo Tea should will be ingested 3 times per day for 3 months |
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| Herbal Tea 2 | Experimental | Experimental Herbal Tea A will be ingested 3 times per day for 3 months |
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| Herbal Tea 3 | Experimental | Experimental Herbal Tea B will be ingested 3 times per day for 3 months |
|
| Herbal Tea 4 | Experimental | Experimental Herbal Tea C will be ingested 3 times per day for 3 months |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Herbal Teas | Other | Steeped tea ingested 3 times a day for 3 mos |
|
| Measure | Description | Time Frame |
|---|---|---|
| The Effect of 3 month Herbal Tea on Changes in Human Type 1 Collagen C-telopeptide (CTx) levels | Urinary CTx levels will be measured at times month 0 (baseline) and month 3 | 3 months |
| The Effect of 3 month Herbal Tea on Changes in Human Procollagen Type 1 Intact N-terminal Propeptide (Total P1NP) levels | Urinary P1NP levels will be measured at times month 0 (baseline) and month 3 | 3 months |
| The Effect of 3 month Herbal Tea on Changes in the Ratio of CTx:P1NP | Urinary CTx:P1NP levels will be measured at times month 0 (baseline) and month 3 | 3 months |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Paula A Witt-Enderby, PhD | Duquesne University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Duquesne University | Pittsburgh | Pennsylvania | 15282 | United States |
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| Label | URL |
|---|---|
| Study assessing the efficacy of herbal teas on bone health and quality of life in a population with osteopenia: rooibos actions on melatonin and tulsi actions on quality of life. | View source |
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| ID | Term |
|---|---|
| D001851 | Bone Diseases, Metabolic |
| ID | Term |
|---|---|
| D001847 | Bone Diseases |
| D009140 | Musculoskeletal Diseases |
| D008659 | Metabolic Diseases |
| D009750 | Nutritional and Metabolic Diseases |
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| ID | Term |
|---|---|
| D000069459 | Teas, Herbal |
| ID | Term |
|---|---|
| D028321 | Plant Preparations |
| D001688 | Biological Products |
| D045424 | Complex Mixtures |
| D001628 | Beverages |
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| D000066888 |
| Diet, Food, and Nutrition |
| D010829 | Physiological Phenomena |
| D019602 | Food and Beverages |