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This study is to compare the short-term and long-term outcomes of traditional laparoscopy-assisted surgery and total laparoscopic surgery with no incision (natural orifice transluminal endoscopic surgery, NOSES) for colorectal cancer and to find a better surgical method for patients.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| traditional laparoscopy-assisted surgery | Active Comparator | The traditional laparoscopic operation undergo and then a small incision(5cm) is made in the middle of the lower abdominal wall to trim the mesangial membrane and remove the specimen. At last the anastomosis operation undergo by the laparoscopic operation. |
|
| total laparoscopic surgery with no incision (NOSES) | Experimental | The whole procedures undergo by total laparoscopic surgery with no incision in the abdominal wall. The specimen then will be removed through natural orifice such as anal. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| traditional laparoscopy-assisted surgery | Procedure | All surgical procedures will be performed by the surgery team ,which is leaded by professor Sun Dong-Hui and Wang Quan. The traditional laparoscopic operation undergo and then a small incision(5cm) is made in the middle of the lower abdominal wall to trim the mesangial membrane and remove the specimen. At last the anastomosis operation undergo by the laparoscopic operation. |
| Measure | Description | Time Frame |
|---|---|---|
| the incidence of complications | All postoperative complications in the perioperative period will be classified by the Clavien-Dindo classification.The classification mainly focuses on the medical perspective, with major emphasis on the risk and invasiveness of the therapy used to correct a complication. From light to heavy, it consists of five grades (â… to â…¤) | one month after surgery |
| Measure | Description | Time Frame |
|---|---|---|
| the operation time | The descriptive name of unit would be minute (min). | in the perioperative period |
| the blood loss during the operation | The descriptive name of unit would be millilitre (ml). |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Dong Yang, Master | Contact | 714488468@qq.com | ||
| Quan Wang, Doctor | Contact | 043181875602 | wangquanjdyy@163.com |
| Name | Affiliation | Role |
|---|---|---|
| Dong-Hui Sun, Doctor | The First Hospital of Jilin University | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| the First Hospital of Jilin University | Recruiting | Ch’ang-ch’un | Jilin | 130021 | China |
There is no plan to make individual participant data (IPD) available to other researchers.
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|
| total laparoscopic surgery with no incision (natural orifice transluminal endoscopic surgery, NOSES) | Procedure | All surgical procedures will be performed by the surgery team ,which is leaded by professor Sun Dong-Hui and Wang Quan. The whole procedures undergo by total laparoscopic surgery with no incision in the abdominal wall. The specimen then will be removed through natural orifice (anal). |
|
| in the perioperative period |
| Postoperative recovery of intestinal peristalsis | The descriptive name of unit would be hour (h). | in the perioperative period |
| Visual Analogue Scale/Score | A Visual Analogue Scale (VAS) is a measurement instrument that tries to measure a characteristic or attitude that is believed to range across a continuum of values and cannot easily be directly measured.It is often used in epidemiologic and clinical research to measure the intensity or frequency of various symptoms.For example, the amount of pain that a patient feels ranges across a continuum from none to an extreme amount of pain ( from 0 to 10). | in the perioperative period |
| the functional outcome of defecation, if there is incontinence | Anal incontinence was evaluated using the Wexner Continence Grading Scale , the score being calculated after the patients' completion of a daily defecatory questionnaire. Range is from 0 (normal continence) to 20 (maximum incontinence with maximum disturbance of lifestyle). | Three months after operation |
| 3-year disease-free survival | three years after operation |
| cases converted to laparotomy | The procedure for cases who underwent laparoscopy-assisted surgery or NOSES can not go successfully, and then it will be converted to laparotomy. The number of all those cases should be recorded. | in the perioperative period |
| The mean postoperative hospital stay | The descriptive name of unit would be day (d). | in the perioperative period |
| ID | Term |
|---|---|
| D057605 | Natural Orifice Endoscopic Surgery |
| ID | Term |
|---|---|
| D004724 | Endoscopy |
| D003949 | Diagnostic Techniques, Surgical |
| D019937 | Diagnostic Techniques and Procedures |
| D003933 | Diagnosis |
| D019060 | Minimally Invasive Surgical Procedures |
| D013514 | Surgical Procedures, Operative |
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