Pregabalin Stabilize Cardiovascular Response to Intubation

Research of Pregabalin Stabilize Cardiovascular Response to Laryngoscopy and Tracheal Intubation of Patients Under General Anesthesia

The purpose of the study is to evaluate whether Pregabalin is safe and effective in stabilizing cardiovascular response to laryngoscopy and tracheal intubation of patients under general anesthesia.

Inclusion Criteria:

• American Society of Anesthesiologists(ASA) grade I and II scheduled for elective surgery

Exclusion Criteria:

• patient refusal.
• patients with serious chronic kidney, liver, lungs, or cardiovascular diseases.
• allergy to any of the study medications.
• patients taking sedation or antihypertensive medications.
• suspected difficult intubation or intubation time more than 22s.
• pregnant or breastfeeding women.
• BMI>30.