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Collapsibility (CI-IVC), distensibility (dIVC) and delta (ΔIVC) indices, which are dynamic measures of inferior vena cava (IVC) diameter, are used to assess the intravascular volume status in critically ill patients. Positive pressure support (PS) has been shown to induce IVC diameter distention by increasing intrathoracic pressure, and high positive expiratory pressure (PEEP) decreases the CI-IVC percentage (4). During Triggered positive pressure support it is necessary to clarify which IVC index is valid for measuring the volume status.it is aimed to compare the IVC indexes (CI-IVC, DIVC, ΔIVC), positive rate of change with pressure, correlation with central venous pressure and accurate prediction of volume status in patients with different positive pressure support.
The IVC diameters at different pressure supports were measured by the same clinician after obtaining a clear image of where the US and IVC measurements were made and the probe stabilization was achieved. He performed the procedure of changing the pressure supports, a blind independent intensive care physician without working, and recorded the applied pressure supports respectively. The different pressure supports applied are as follows:
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| PS 10 mmHg, PEEP 5 mmHg | IVC diametres, CI-IVC, distensibility and delta index measurements using by ultrasound. Central venous pressure correlation with IVC index |
| |
| PS 10 mmHg PEEP 0 mmHg | IVC diametres, CI-IVC, distensibility and delta index measurements using by ultrasound. Central venous pressure correlation with IVC index |
| |
| PS 0 mmHg PEEP 5 mmHg | IVC diametres, CI-IVC, distensibility and delta index measurements using by ultrasound. Central venous pressure correlation with IVC index |
| |
| t tube (PS 0 mmHg PEEP 0mmHg) | IVC diametres, CI-IVC, distensibility and delta index measurements using by ultrasound. Central venous pressure correlation with IVC index |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| IVC diametres | Other |
|
| Measure | Description | Time Frame |
|---|---|---|
| Determine the effect of positive pressure on IVC collapsibility index | Determine the effect on CI-IVC of an increase in positive end-expiratory pressure and pressure support | 12 month |
| Determine the effect of positive pressure on IVC distensibility index | Determine the effect on distensibility index of an increase in positive end-expiratory pressure and pressure support | 12 month |
| Determine the effect of positive pressure on IVC delta index | Determine the effect on delta index of an increase in positive end-expiratory pressure and pressure support | 12 month |
| Measure | Description | Time Frame |
|---|---|---|
| Determine the effect of positive pressure on central venous pressure | Determine the effect on central venous pressure of an increase in positive end-expiratory pressure and pressure support | 12 month |
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Inclusion Criteria:
Exclusion Criteria:
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Inpatient sample
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| Name | Affiliation | Role |
|---|---|---|
| Tepecik Training and Research Hospital | Tepecik Training and Research Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Tepecik Research and Training Hospital | Izmir | Konak | 35110 | Turkey (Türkiye) |
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| ID | Term |
|---|---|
| D012131 | Respiratory Insufficiency |
| ID | Term |
|---|---|
| D012120 | Respiration Disorders |
| D012140 | Respiratory Tract Diseases |
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| ID | Term |
|---|---|
| D002496 | Central Venous Pressure |
| ID | Term |
|---|---|
| D014690 | Venous Pressure |
| D001794 | Blood Pressure |
| D006439 | Hemodynamics |
| D002320 | Cardiovascular Physiological Phenomena |
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| D002943 |
| Circulatory and Respiratory Physiological Phenomena |