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A question is raised about the possibility of accurate localization of the SLN (sentinel lymph node) detected by CTLG (Computed Tomography Lymphography) which offers a detection rate of 100% in many studies In Oncology center, Mansoura University (OCMU), the surgical oncology unit had a previous experience in using charcoal for localization of non-palpable suspicious breast lesions and it showed promising results in comparison to traditional localization methods In addition, we had another study using silver wire for localization of breast masses before neoadjuvant therapy.
In the study, the investigators will study the usage of both methods as preoperative localization methods for the SLN detected by CT lymphography in breast cancer patients The investigators suppose that this method can offer two main advantages over the traditional SLN intraoperative methods which are; saving operative time needed for the intraoperative procedure as well as solving the problem of the need for complex logistic preparations especially for the usage of radioisotope method.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| charcoal | Experimental |
| |
| silver wire | Experimental |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| preoperative localization of SLN detected by CTLG by either methods | Device | 50 patients with node negative early breast cancer. The patients were randomized into two groups; SLN localized using CTLG guided injection of liquid charcoal suspended solution (first group) or by placing a 3 cm silver wire using spinal needle (second group). For every patient, SLN biopsy was performed using the traditional method with blue dye. Then dual search for the SLN localized by both the novel & traditional method was performed. |
| Measure | Description | Time Frame |
|---|---|---|
| detection of the sentinel lymph node by the novel method & matching between the sentinel lymph node detected by the novel method and the control one | one year |
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Inclusion Criteria:
Exclusion Criteria:
• Unfit patients for general anaesthesia
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Omar Hamdy, MSc | Contact | +201003526752 | omarhamdy87@gmail.com |
| Name | Affiliation | Role |
|---|---|---|
| Omar Hamdy, MSc | Oncology center, Mansoura University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Oncology center, Mansoura University | Recruiting | Al Mansurah | 35611 | Egypt |
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|
| ID | Term |
|---|---|
| D001943 | Breast Neoplasms |
| ID | Term |
|---|---|
| D009371 | Neoplasms by Site |
| D009369 | Neoplasms |
| D001941 | Breast Diseases |
| D012871 | Skin Diseases |
| D017437 | Skin and Connective Tissue Diseases |
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