Impact of Rutin and Vitamin C Combination on Oxidative Stress, Insulin Sensitivity and Lipid Profile in Type 2 Diabetic Patients

Evaluation of the Impact of Rutin and Vitamin C Combination on Oxidative Stress, Insulin Sensitivity and Lipid Profile in Type 2 Diabetic Patients

The objective of this study is to investigate the effect ofRutin and Vitamin C combination in comparison with vitamin C alone on the oxidative and antioxidative status , insulin resistance and lipid profile in type 2 diabetic patients.

Inclusion Criteria:

• • Patients' age 35 years or older having type 2 diabetes mellitus.

  • Patients taking oral diabetic medications (Sulfonylurea) not taking Insulin.
  • Able to understand and willing to sign a written informed consent document

Exclusion Criteria:

• • Pregnant and breast feeding females

  • use of vitamin supplements containing vitamin C or other antioxidants.

• patients with renal or hepatic failure.

• patients taking insulin as antidiabetic treatment