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| ID | Type | Description | Link |
|---|---|---|---|
| 912180 | Other Identifier | CNIL number | |
| 12-272 | Other Identifier | CCTIRS number |
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| Name | Class |
|---|---|
| Ministry of Health, France | OTHER_GOV |
| Ligue contre le cancer, France | OTHER |
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Evaluate the reproducibility and validate a posteriori a new rule of clinical decision on a multi-center population of children with a post-chemotherapy febrile neutropenia
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| Measure | Description | Time Frame |
|---|---|---|
| Blood culture | Presence or not of bacteriemia | On average between 5 days and 1 month |
| Positive bacterial culture from a normally sterile site | Presence or not of bacterial infection | on average between 5 days and 1 month |
| microbiological culture | Presence or not of focal infection at high risk of dissemination was defined as any local infection with or without microbiological documentation into a normally sterile site, with significant risk of loco-regional or systemic spread | On average between 5 days and 1 month |
| Fungal culture | Presence or not of fungal infection is referred to a proven, probable, or possible fungal infection as defined by the IFICG ot the EORTC | On average between 5 days and 1 month |
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Inclusion Criteria:
Exclusion Criteria:
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Patient with hematology or cancer who consults for febrile neutropenia post-chemotherapy
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| Name | Affiliation | Role |
|---|---|---|
| François Dubos, MD, PhD | University Hospital, Lille | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Hôpital Jeanne de Flandre - CHRU de Lille | Lille | France |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 34871572 | Result | Delebarre M, Gonzales F, Behal H, Tiphaine A, Sudour-Bonnange H, Lutun A, Abbou S, Pertuisel S, Thouvenin-Doulet S, Pellier I, Mansuy L, Piguet C, Paillard C, Blanc L, Thebaud E, Plantaz D, Blouin P, Schneider P, Guillaumat C, Simon P, Domenech C, Pacquement H, Le Meignen M, Pluchart C, Verite C, Plat G, Martinot A, Duhamel A, Dubos F. Decision-tree derivation and external validation of a new clinical decision rule (DISCERN-FN) to predict the risk of severe infection during febrile neutropenia in children treated for cancer. Lancet Child Adolesc Health. 2022 Apr;6(4):260-268. doi: 10.1016/S2352-4642(21)00337-0. Epub 2021 Dec 3. |
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| ID | Term |
|---|---|
| D064147 | Febrile Neutropenia |
| ID | Term |
|---|---|
| D009503 | Neutropenia |
| D000380 | Agranulocytosis |
| D007970 | Leukopenia |
| D000095542 | Cytopenia |
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| D006402 |
| Hematologic Diseases |
| D006425 | Hemic and Lymphatic Diseases |
| D007960 | Leukocyte Disorders |