FENO, Extended NO Analysis and NO/CO Diffusing Capacity in Thoracic Radiation Therapy

Fractional Exhaled NO, Extended NO Analysis and NO/CO Diffusing Capacity in Patients Receiving Thoracic Radiation Therapy: a Single Centre Study

The investigators aim to investigate the impact of thoracic radiation therapy on diffusion capacity of the lung (primary endpoint: diffusion capacity for nitric oxide, DLNO) and on exhaled nitric oxide.

Inclusion Criteria:

• planned but not already commenced radiation therapy (RT) of the chest, with or without pre-RT surgery.
• signed informed consent of the participant

Exclusion Criteria:

• thoracic RT in the past
• treatment with immune checkpoint inhibitors
• unstable condition affecting participation in the measurements