Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
The primary purpose of this study is to compare pain after uterine artery embolization using non-spherical polyvinyl alcohol particles or tris-acryl gelatin microsphere in patients with symptomatic fibroids
Uterine artery embolization(UAE) is a minimally invasive treatment alternative to hysterectomy and myomectomy in symptomatic fibroids. However, post-procedural pain after UAE remains a major problem. The non-spherical polyvinyl alcohol particle and tri-acryl gelatin microsphere are two embolic materials used for UAE.Therefore, the aim of study is to compare pain intensity and inflammation after uterine artery embolization using non-spherical polyvinyl alcohol particles or tris-acryl gelatin microsphere in patients with symptomatic fibroids
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Non-spherical polyvinyl alcohol particle | Experimental | For embolic material, non-spherical polyvinyl alcohol particle is used. |
|
| Tris-acryl gelatin microsphere | Experimental | For embolic material, Tris-acryl gelatin microsphere is used. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Non-spherical polyvinyl alcohol particle or Tris-acryl gelatin microsphere | Device | One of non-spherical polyvinyl alcohol particle or tris-acryl gelatin microsphere is used for embolic materials. All other processes are same. |
| Measure | Description | Time Frame |
|---|---|---|
| Pain intensity by numerical rating scale | 0-10 numerical rating scale (0, no pain at all; 10, worst pain imaginable | 0-24 h after UAE |
| Measure | Description | Time Frame |
|---|---|---|
| C-reactive protein | mg/L | 24 h after UAE |
| White blood cell count | /uL | 24 h after UAE |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Affiliation | Role |
|---|---|---|
| So Yeon Kim, MD, PhD | Department of Anesthesiology and Pain Medicine, Anesthesia and Pain Research Institute, Severance Hospital, Yonsei University College of Medicine | Principal Investigator |
| Man Deuk Kim, MD, PhD | Department of Radiology, Research Institute of Radiological Science, Severance Hospital, Yonsei University College of Medicine | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Sesverance Hospital, Yonsei University College of Medicine | Seoul | 03722 | South Korea |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| ID | Term |
|---|---|
| D007889 | Leiomyoma |
| ID | Term |
|---|---|
| D009379 | Neoplasms, Muscle Tissue |
| D018204 | Neoplasms, Connective and Soft Tissue |
| D009370 | Neoplasms by Histologic Type |
| D009369 | Neoplasms |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Neutrophil percentage | 24 h after UAE |
| Neutrophil-to-lymphocyte ratio | 24 h after UAE |
| Platelet-to-lymphocyte ratio | 24 h after UAE |
| Mean platelet volume | fL(femtolitre) | 24 h after UAE |
| Sucessful rate at 3 month after UAE measured by MRI | Complete necrosis incidence | 3 month after UAE |