Nutrition and Outcomes of Hematopoietic Cell Transplantation (HCT)

Route and Adequacy of Nutrition and Outcomes of Haematopoietic Cell Transplantation in Patients With Haematological Neoplasms

Retrospective case-note review to determine if nutrition via the enteral compared to the parenteral route results in better outcomes after haematopoietic cell transplantation.

This is a retrospective case-note review of adults undergoing haematopoietic cell transplantation to treat a haematological malignancy who have been admitted to Hammersmith Hospital from 2000 to 2014. All patients receiving an allogeneic haematopoietic cell transplant from a matched sibling or identically matched unrelated donor will be included. We will record the route and assess the broad adequacy of nutritional intakes to determine if nutrition via the enteral compared to the parenteral route results in better outcomes after haematopoietic cell transplantation. Our outcomes are graft versus host disease incidence and severity, transplant related (early) mortality and overall survival.

Inclusion Criteria:

• Patients undergoing their first HCT for a hematologic malignancy
• Undergoing HCT using a sibling or unrelated donor
• Undergoing HCT infusion between January 2000 and December 2014

Exclusion Criteria:

• HCT using umbilical cord blood donors
• HCT using haploidentical donors