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| Name | Class |
|---|---|
| Welch's Food Corporation | UNKNOWN |
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Assess the impact of 100% grape juice on postprandial glycemic response and subsequent appetite, food intake and cognitive function.
Investigators earlier clinical work and published literature suggest that the phenolic content and strong flavor intensity of 100% Concord grape juice hold potential beneficial effects on appetite and glycemia. Investigators aim to better understand the use of 100% grape juice modifies appetite and glycemia acutely and over the day using a 24 hour glucose monitor.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Concord Grape Juice | Active Comparator | 100% Concord Grape Juice |
|
| Low flavonoid low essence beverage | Sham Comparator | Low flavonoid low essence beverage |
|
| Low flavonoid beverage | Sham Comparator | Low flavonoid beverage |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Concord Grape Juice | Other | Concord Grape Juice |
| |
| Measure | Description | Time Frame |
|---|---|---|
| Change in blood glucose over 24 hours | samples taken every 5 minutes for 24 hours by a continuous glucose monitor | 24 hours |
| Measure | Description | Time Frame |
|---|---|---|
| Appetite | Questionnaire on hunger, fullness, desire to eat, prospective consumption, thirst taken hourly on same day as grape juice intervention | 24 hours |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Richard D Mattes, PhD | Purdue University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Purdue University | West Lafayette | Indiana | 47909 | United States |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 34698750 | Derived | Coelho OGL, Alfenas RCG, Debelo H, Wightman JD, Ferruzzi MG, Mattes RD. Effects of Concord grape juice flavor intensity and phenolic compound content on glycemia, appetite and cognitive function in adults with excess body weight: a randomized double-blind crossover trial. Food Funct. 2021 Nov 15;12(22):11469-11481. doi: 10.1039/d1fo02049h. |
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| ID | Term |
|---|---|
| D001070 | Appetitive Behavior |
| ID | Term |
|---|---|
| D001522 | Behavior, Animal |
| D001519 | Behavior |
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| Low flavoniod low essence beverage |
| Other |
Low flavoniod low essence beverage |
|
| Low flavonoid beverage | Other | Low flavonoid beverage |
|