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The use of progestin-only methods of contraception has been increased obviously and progressively over the world in the last few years. Progestin-only contraception is an option for women in whom an estrogen-containing contraceptive is either contraindicated or causes additional health concerns.
Progestogen-only pills are contraceptive pills that contain only synthetic progestogens (progestins) and do not contain estrogen . The progestin-only pill is recommended over regular birth control pills for women who are breastfeeding because the mini-pill does not affect milk production.
The most common progestin-only method used is the injectable depot medroxy-progesterone acetate which had been approved by Food and Drug Administration since 1992 . depot medroxy-progesterone acetate provides reliable, private, long-acting (three months) and reversible contraception. Users of depot medroxy-progesterone acetate don't need daily taking as well as it doesn't affect the intercourse by any mean.
The etonogestrel implant (Implanon) is a single-rod progestin contraceptive method placed subdermally in the inner aspect of upper non dependant arm for three years. Much evidence supports the safety, efficacy, reversibility and acceptability of this contraceptive method.
A common reason women choose to discontinue progestin-only contraception is dissatisfaction with its effects on uterine bleeding which occurs in a significant number of users. Information revealed from many clinical trials shows that abnormal uterine bleeding with progestin-only contraception ranging from 10 to 25 % at first year of use.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Group I "the depot medroxy-progesterone acetate group" | where they will use Depot Medroxyprogesterone Acetate 150 mg injection every 3 month, |
| |
| Group II "Implanon group" | where they will have Implanon (etonogestrel implant) 68 mg implant |
| |
| group III (cerazette group) | where they are using Cerazette pills (desogestrel 75 µg l) one pill every day for 28 days without pill-free interval. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Depot medroxy-progesterone acetate | Drug | Injection every 3 months |
|
| Measure | Description | Time Frame |
|---|---|---|
| Number of women developed vaginal bleeding | 12 month |
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Inclusion Criteria:
Exclusion Criteria:
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women who requested DMPA, etonogestrel subdermal implant or POPs for pregnancy prevention.
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Women Health Hospital - Assiut university | Asyut | 71111 | Egypt |
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| ID | Term |
|---|---|
| C044815 | etonogestrel |
| D017135 | Desogestrel |
| ID | Term |
|---|---|
| D009652 | Norpregnenes |
| D009650 | Norpregnanes |
| D009654 | Norsteroids |
| D013256 | Steroids |
| D000072473 |
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| Etonogestrel | Drug | 68 mg implant |
|
| Desogestrel 75 µg | Drug | one pill every day for 28 days without pill-free interval. |
|
| Fused-Ring Compounds |
| D011083 | Polycyclic Compounds |