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Investigate the effect of 12 weeks mixed power training (power and functional exercises) combined with a protein supplementation (30g/d) or not (placebo) on physiological characteristics of muscle and functional capacities in elderly men.
Life habits are know to be able to prevent the loss of functional capacities and muscle function during aging process. More specifically, protein intake is important to maintain muscle function in older adults. Another non pharmacological intervention and well recognized for its efficacy, it's exercise training.
Recently, it has been observed than muscle quality is more important to maintain physical autonomy than muscle mass per se. In addition, muscle quality is more related to functional capacities than muscle mass.
Due to this recent finding, it has been proposed that muscle power training would be the best exercise intervention to prevent the loss of mobility.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Exercise + Placebo group | Active Comparator | 50 subjects will receive a placebo supplementation with an exercise intervention (EX group) |
|
| Exercise + Protein group | Active Comparator | 50 subjects will receive a protein supplementation combined with an exercise intervention (PROTEX group) |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Exercise + Placebo group | Other | 1/2 of the subject will follow a mixed power training: 4 power exercises + 6 functional exercises combined to a placebo |
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| Measure | Description | Time Frame |
|---|---|---|
| Change in walking speed | evaluate using the 4m- normal walking speed (m/sec) | Change from Baseline walking speed at 12 weeks measure in all subjects |
| Measure | Description | Time Frame |
|---|---|---|
| Change in lower limb muscle quality | Knee extension muscle strength (isometric (N)/ lower limb muscle mass (kg)) | Change from Baseline lower limb muscle quality at 12 weeks measure in all subjects |
| Measure | Description | Time Frame |
|---|---|---|
| Change in mitochondrial activity | citrate synthase activity (unit: percent) | Change from Baseline mitochondrial activity at 12 weeks measure in half of the subjects |
Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| mylene aubertin-leheudre, PhD | Université du Québec a Montréal | Principal Investigator |
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| ID | Term |
|---|---|
| D009043 | Motor Activity |
| ID | Term |
|---|---|
| D001519 | Behavior |
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| ID | Term |
|---|---|
| D015444 | Exercise |
| ID | Term |
|---|---|
| D009043 | Motor Activity |
| D009068 | Movement |
| D009142 | Musculoskeletal Physiological Phenomena |
| D055687 | Musculoskeletal and Neural Physiological Phenomena |
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| Exercise + Protein group | Other | 1/2 of the subject will receive 30 g/ d of protein (leucine+ vitD; divided in three equal doses: morning, afternoon and evening) + will follow a mixed power training: 4 power exercises + 6 functional exercises. |
|