Shanghai Infants Gut Microbiome Associated Study

Effects of Probiotics on the Gut Microbiome of Infants Treated With Antibiotics

The purpose of this study is to evaluate the effect of probiotics on the gut microbiome of infants treated with antibiotics.

This study aims to examin the impact of probiotics under 2 separate conditions, probiotics concurrent administration with antibiotic and probiotics administration during the recovery phase.Birth,7 days,14 days(or 21 days) and 42 days data will be collected and put into analysis to provide somes suggestions on the probiotics use in the clinical for the infants treated with antibiotics.

Inclusion Criteria:

• Newborns with infectious diseases treated with antibiotic

Exclusion Criteria:

• Gestational weeks <37
• Birth weight <2500g or ≥4000g
• History of asphyxia anoxia at birth
• With congenital metabolic diseases or hereditary diseases
• With gastrointestinal diseases