Radiofrequency Ablation Using Octopus Electrodes for Small Hepatocellular Carcinoma With No-touch Technique

Radiofrequency Ablation Using Octopus Electrodes for Small Hepatocellular Carcinoma With No-touch Technique: A Prospective Single Arm Study

The aim of this study is to evaluate clinical outcome of RFA for small single nodular HCC using no touch technique with separable clustered electrode (Octopus) in a prospective multicenter manner Participating center: Seoul national university hospital, Asan medical center, Samsung medical center, Kunkuk university hospital, St. mary's Seoul hospital

Inclusion Criteria:

• Child-Pugh class A liver function
• 1 - 2.5 cm sized Single nodular HCC
• without history of previous HCC treatment or with evidence of no recurrence at least 2 years after previous HCC treatment

Exclusion Criteria:

• more than 2 HCC
• tumor size larger than 2.5 cm
• Child-Pugh class B or C liver function
• invisible tumor even after real-time fusion US guidance
• accompanied by vascular invasion or distant metastasis
• presence of coagulopathy defined as platelet count < 50,000/mm3 and/or PT-INR > 50%