Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Regular sustained physical activity creates a cardiac remodelling : it is athlete's heart. In our preliminary work published in 2016, the investigators demonstrated in a small population of triathletes that there is also a vascular remodelling named athlete's artery. Moreover, the investigators know that left ventricle and aorta behave together like a couple. So they want to study by Cardiovascular Magnetic Resonance Imaging the impact of triathlon on the cardiac AND aortic remodelling.
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Triathletes | Experimental | Every triathlete will realize three cardiac MRI exams.The second of those will be done at the fitness peak, 2-3 weeks before the main objective of the sports season. Training will be increased between the study beginning and the first MRI, and the second exam. After each cardiac MRI, an applanation tonometry examination will aslo be performed. |
|
| Controls | Experimental | Every control subject will also realize three cardiac MRI exams if possible at the same time as the triathletes.They must be not engaged in physical activity more than 150 minutes a week on average. After each cardiac MRI, an applanation tonometry examination will aslo be performed. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Cardiac MRI | Device | Non injected cardiac MRI exam |
| |
| Measure | Description | Time Frame |
|---|---|---|
| Aortic compliance in triathletes in mm2/mmHG | aortic compliance = pulsed pressure-to-absolute variation of aortic surface ratio | at baseline, at the fitness peak (6 to 10 months later) and at recovery (3 to 6 months after the fitness peak) |
Not provided
Not provided
Inclusion Criteria:
to be enrolled in a social security plan.
to have a BMI between 18,5 and 25 kg/m²
to have received full information on the organization of the research and having signed its informed consent
to have carried out a clinical screening adapted to the research
*** Triathlete group:
to have a minimum performance level: between 2h and 2h45 on an M triathlon during the past year (provide proof),
to participate in 2018 in a long distance triathlon, i. e. at least distance L
to have a defined training volume: less than 8 hours per week during the winter months and between 10 and 15 hours per week in preparation of the objective
***Control group:
to have no more than 150 minutes of moderate physical activity per week (footing, brisk walking, cycling, etc.).
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Affiliation | Role |
|---|---|---|
| Damien MANDRY, MD,PhD | CHRU de Nancy | Principal Investigator |
| Anne-Charlotte DUPONT, MD | CHRU de Nancy | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Central Hospital | Nancy | 54000 | France |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 27838232 | Background | Dupont AC, Poussel M, Hossu G, Marie PY, Chenuel B, Felblinger J, Mandry D. Aortic compliance variation in long male distance triathletes: A new insight into the athlete's artery? J Sci Med Sport. 2017 Jun;20(6):539-542. doi: 10.1016/j.jsams.2016.10.009. Epub 2016 Oct 29. |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Applanation tonometry |
| Device |
Applanation tonometry and ECG |
|
| ID | Term |
|---|---|
| D020257 | Ventricular Remodeling |
| D066253 | Vascular Remodeling |
| ID | Term |
|---|---|
| D020763 | Pathological Conditions, Anatomical |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D010335 | Pathologic Processes |
Not provided
Not provided