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The purpose of this study is to evaluate if there are differences in oocyte quality depending on whether these oocytes come from an ovary in contact with an endometrioma.
There is no consensus for whether an endometrioma influences oocyte quality, as well as the possible mechanisms that induce them.
In this study, the oocyte maturation will proof oocyte quality: This mean, the percentage of oocytes in metaphase II obtained after stimulation, as well as the rate of oocytes fertilized in direct contact with an endometrioma.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Endometriosis | No drugs are administered. It is an observational study. Collect retrospectively data |
| |
| No endometriosis | No drugs are administered. It is an observational study. Collect retrospectively data |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Collect retrospectively data | Other | Collect retrospectively data |
|
| Measure | Description | Time Frame |
|---|---|---|
| Percentage of mature oocytes | Number of MII oocytes from the total of cumulus granulosa cell-oocyte complex by 100 | Up to 36 months |
| Fertilization rate | Number of oocytes with pronuclear activation after ICSI procedure from the total oocytes microinjected by 100 | Up to 36 months |
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Inclusion Criteria:
Exclusion Criteria:
-
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Patients <40 years, BMI <30kg / m2,
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| Name | Affiliation | Role |
|---|---|---|
| Elkin Muñoz, Principal Investigator | IVI Vigo | Principal Investigator |
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| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 15136074 | Background | Garcia-Velasco JA, Mahutte NG, Corona J, Zuniga V, Giles J, Arici A, Pellicer A. Removal of endometriomas before in vitro fertilization does not improve fertility outcomes: a matched, case-control study. Fertil Steril. 2004 May;81(5):1194-7. doi: 10.1016/j.fertnstert.2003.04.006. | |
| 10711831 | Background | Garrido N, Navarro J, Remohi J, Simon C, Pellicer A. Follicular hormonal environment and embryo quality in women with endometriosis. Hum Reprod Update. 2000 Jan-Feb;6(1):67-74. doi: 10.1093/humupd/6.1.67. |
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| ID | Term |
|---|---|
| D004715 | Endometriosis |
| ID | Term |
|---|---|
| D005831 | Genital Diseases, Female |
| D052776 | Female Urogenital Diseases |
| D005261 | Female Urogenital Diseases and Pregnancy Complications |
| D000091642 | Urogenital Diseases |
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| 24602751 | Background | Filippi F, Benaglia L, Paffoni A, Restelli L, Vercellini P, Somigliana E, Fedele L. Ovarian endometriomas and oocyte quality: insights from in vitro fertilization cycles. Fertil Steril. 2014 Apr;101(4):988-93.e1. doi: 10.1016/j.fertnstert.2014.01.008. Epub 2014 Mar 3. |
| D000091662 | Genital Diseases |