Changes in Renal Papillary Density After Hydration Therapy in Calcium Stone Formers

Changes in Renal Papillary Density After Hydration Therapy in Calcium Stone Formers

Patients with recurrent calcium oxalate stones undergoing endourological procedures for renal stones at our institution from June 2013 to June 2014 were considered eligible for enrolment. Enrolled patients underwent a baseline unenhanced CT scan before the urological procedure; after endoscopic removal of their stones, the patients were instructed to drink at least 2 L/day of a hypotonic, oligomineral water low in sodium and minerals (fixed residue at 180°C <200 mg/L) for at least 12 months. Finally, the patients underwent a follow-up unenhanced CT scan during hydration regimen.

Inclusion Criteria:

• Patients undergoing endourological procedures for renal stones
• Recurrent stone disease
• Calcium oxalate stones (>50% of the stone made of calcium oxalate)

Exclusion Criteria:

• Systemic conditions causing stones (hyperparathyroidism, intestinal malabsorption, renal tubular acidosis)
• Non-calcium oxalate stones