Mometasone vs Budesonide in CRS With Polyposis

Randomized Controled Double-blinded Study Comparing Mometasone Nasal Spray to Budesonide Irrigations in Patients With Chronic Rhinosinusitis With Nasal Polyposis

The principal objective is to compare the use of mometasone nasal spray to budesonide irrigations in patients suffering from CRSwNP who have never been operated.

Inclusion Criteria:

• Diagnosis of chronic rhinosinusitis with nasal polyps
• Absence of active infection at start of study

Exclusion Criteria:

• Diagnosis of chronic rhinosinusitis without nasal polyps
• Diagnosis of recurrent acute bacterial rhinosinusitis
• Previous sinus surgery (septal of inferior turbinate surgeries are not considered sinus surgeries)
• Cystic fibrosis or ciliary dyskinesia
• Allergy to corticosteroids
• Pregnant or lactating women
• Contra-indication to intranasal steroids