Regulation of Metabolism and Ion Handling

Regulation of Metabolism and Ion Handling - Effect of High Intensity Training and NAC-infusion in Young Men

This study investigates the relation between ion-handling (K+) and fatigue development during exercise. Before and after a 6-week period of high intensity interval training, performance and ion-handling is assessed in young adults. In addition, mitochondrial function is examined.

Inclusion Criteria:

• Healthy men
• 45-55 ml/kg/min
• BMI 19-26 kg/m2
• Normal ECG (assessed by MD)

Exclusion Criteria:

• Allergic to n-acetylcystine (NAC) or digoxin
• Severe side effects from NAC or digoxin
• Chronic diseases (assessed by MD to be a potential hazard or to interfere with outcome measures)