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| Name | Class |
|---|---|
| Duquesne University | OTHER |
| University of Nebraska Lincoln | OTHER |
| University of Arizona | OTHER |
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The purpose of this two phase study is to evaluate comprehension by people with acquired brain injury. The phase 1 portion of the study will examine comprehension of narrative paragraphs under 3 conditions: (a) written text only, (b) auditory output only (i.e., synthetic speech - David voice) or combined written text and auditory output. The phase 2 portion of the study is to evaluate comprehension of sentences and paragraphs produced with computer generated (synthesized) speech and digitized natural speech after multiple exposures.
Part 1 Experimental Procedures: Written or Spoken Paragraph Level Measure o Participants will read or listen to 12 paragraph length narrative stories in the following 3 conditions: (a) written text only, (b) auditory output only (i.e., synthetic speech - David), or combined written text and auditory output. Participants will answer 10 questions regarding the information contained in each of the 12 stories. Anticipated time requirements: 1 to 2 sessions lasting about 60 minutes each.
Part 2 Experimental Procedures: Repeated Exposures
Independent Training Session Practice
Independent Training Sessions
Post-Testing Sessions
One Post-Testing Session will occur within 1 week after the last practice session ends. It will last about 60 minutes. Post-Testing tasks include responding to 45 yes/no TOSREC sentences (15 per 3 conditions), selecting a picture following the 45 Norman Rockwell sentence level comprehension task (15 per 3 conditions), and answering questions after listening to two QRI stories from one condition (Synthetic 1).
o Following completion of the procedure above, participants will rate the accuracy and ease of comprehension of the sentences from each condition using a 5-point Likert scale. These questions appear in Appendix G.
The Maintenance Session will occur about 4 weeks after the last practice session ends. It will last approximately 60 minutes. The Maintenance Session tasks include responding to 45 yes/no TOSREC sentences (15 per 3 conditions), selecting a picture following the Norman Rockwell sentence level comprehension task (15 per 3 conditions), and answering questions after listening to two QI stories from one condition (Synthetic 1).
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Comprehension Acquired Brain Injury | Experimental | All participants will be exposed to 3 conditions: (a) written text, (b) auditory output (synthetic speech), and combined conditions for study 1. For study 2 participants will be repeatedly exposed to synthetic speech output to determine the influence on comprehension. Participants are not required to participate in both studies. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Comprehension Acquired Brain Injury | Behavioral | For study 1 participants will be exposed to 3 conditions as stated in previous descriptions and will last 1 to 2 sessions. Study 2 will begin with 1 session with the researcher lasting about 30 minutes. Then participants will be asked to complete practice at home for about 15 minutes each day for 2 weeks using a computer/iPad. Study 2 Post Testing and Maintenance Sessions 1 and 2: approximately 60 minutes per session. |
| Measure | Description | Time Frame |
|---|---|---|
| Comprehension Across Conditions (Study 1 of 2) | Participants will answer 10 multiple choice questions regarding the information contained in each of the 12 stories presented in 3 conditions: (1) written text only (b) auditory output only and (c) combined written text and auditory output . | Comprehension accuracy across conditions will be assessed over 1 to 2 days. |
| Repeated Exposure to Digitized and Synthetic Speech (Study 2 of 2) | Participants will answer 30 yes/no questions per session. Comprehension percentage accuracy will be measured over the course of 2 weeks | 2 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Comprehension Generalization | Participants will listen to two stories presented in synthetic, computer generated speech and answer comprehension questions about the content of the stories to determine auditory comprehension accuracy | measured 1 week and 4 weeks post termination of treatment |
| Perceived Comprehension Accuracy |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Kelly K Knollman-Porter, PhD | Contact | 7652653640 | knollmkk@miamioh.edu | |
| Sarah Wallace, PhD | Contact | 4123964219 | wallaces@duq.edu |
| Name | Affiliation | Role |
|---|---|---|
| Kelly K Knollman-Porter, PhD | Miami University | Principal Investigator |
| Sarah Wallace, PhD | Duquesne University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Miami University | Recruiting | Oxford | Ohio | 45056 | United States |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| Background | Wagner R. K., Torgesen J. K., Rashotte C. A., Pearson N. A. (2010). Test of Silent Reading Efficiency and Comprehension (TOSREC) examiner's manual. Austin, TX: Pro-Ed. |
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We will not be sharing the data because of possible breach of privacy given the small number of local people with acquired brain injury/stroke.
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| Type | Date | Date Unknown |
|---|---|---|
| Release | Sep 19, 2019 | |
| Reset | Oct 10, 2019 |
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| Release Date | Unrelease Date | Unrelease Date Unknown | Reset Date | MCP Release Number |
|---|---|---|---|---|
| Sep 19, 2019 | Oct 10, 2019 |
| ID | Term |
|---|---|
| D001037 | Aphasia |
| D000070642 | Brain Injuries, Traumatic |
| ID | Term |
|---|---|
| D013064 | Speech Disorders |
| D007806 | Language Disorders |
| D003147 | Communication Disorders |
| D019954 | Neurobehavioral Manifestations |
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During Study 1 participants will be exposed to three different conditions: (a) written text only, (b) auditory synthetic speech output only and (c) a combined condition (written and auditory output). During Study 2 participants will be provided repeated exposure to synthetic speech. Participants can participate in 1 or both studies with 1 study results not being dependent on the other study. .
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|
Participants will rate the accuracy and ease of comprehension of the sentences from each condition using a 5 point Likert scale. |
| measured 1 week and 4 weeks post termination of treatment |
| D009461 | Neurologic Manifestations |
| D009422 | Nervous System Diseases |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D001930 | Brain Injuries |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
| D006259 | Craniocerebral Trauma |
| D020196 | Trauma, Nervous System |
| D014947 | Wounds and Injuries |