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The main purpose of this study is to build a multi-center, prospective and regionally representative acute myocardial infarction(AMI) cohort,and build a study platform for heart failure caused by AMI; To explore the 1 year incidence rate of heart failure after AMI given the optimized treatment and the treatment model affecting the incidence rate of heart failure, and finally to reduce the incidence rate of heart failure by 5%.
the study aim to enroll 12000 acute myocardial infartion (AMI) patients, including ST-segment elevation myocardial infarction (STEMI) and non ST-segment elevation myocardial infarction (NSETMI), Patients were divided into two groups(optimized group and un-optimized group) according to treatment models they accepted in 20 reginally representative hosptials of China. whether optimizaed or not is judged by 4 four aspects,including emergency treatment procedure, pre-infusion medication, reperfusion strategy selection, and early rehabilitation after reperfusion.Patients were followed at 1 month, 6 months and 12 months. The physical condition and clinical events(heart failure, death, re-infarction, revascularization, apoplexy, malignant arrhythmias, bleeding events, other adverse events)were collected at follow up.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| optimized group | the patients in this group have been given the suggestive treatment from guideline. | ||
| un-optimized group | the patients in this group have not been given the suggestive treatment from guideline. |
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| Measure | Description | Time Frame |
|---|---|---|
| incidence rate of heart failure | incidence rate of heart failure of acute myocardial infarction at 12th month | 12th month after diacharge |
| Measure | Description | Time Frame |
|---|---|---|
| MACCE rate | the major adverse cardiac celebral events including death,reinfarction, | 12th month after diacharge |
| bleeding rate | the incidence rate of bleeding |
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Inclusion Criteria:
Exclusion Criteria:
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acute myocadial infarction
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Beijing An Zhen Hospital, Capital Medical University | Beijing | Beijing Municipality | 100029 | China | ||
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 38185283 | Derived | Wang J, Li Z, Yang G, Fang C, Yin Y, Zheng Z, Wang H, Fang S, Dai J, Wang S, Yang S, Yu B. Pseudo-targeted metabolic profile differences between emergency patients with type 1 and type 2 myocardial infarction diagnosed by optical coherence tomography. Clin Chim Acta. 2024 Feb 1;554:117745. doi: 10.1016/j.cca.2023.117745. Epub 2024 Jan 6. | |
| 37104944 |
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| ID | Term |
|---|---|
| D006333 | Heart Failure |
| ID | Term |
|---|---|
| D006331 | Heart Diseases |
| D002318 | Cardiovascular Diseases |
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| 12th month after diacharge |
| severe adverse drug reactions | severe adverse drug reactions at 12th month | 12th month after diacharge |
| Peking Univerisity People'Hospital |
| Beijing |
| Beijing Municipality |
| 100044 |
| China |
| Beijing Chao-Yang Hospital, Capital Medical University | Beijing | Beijing Municipality | China |
| Peking University First Hospital | Beijing | Beijing Municipality | China |
| Guangdong general hospital | Guangzhou | Guangdong | China |
| The first affiliated hospital of Guangxi medical university | Nanning | Guangxi | 530021 | China |
| Second hospital of hebei medical university | Shijiazhuang | Hebei | China |
| Daqing Oilfield General Hospital | Daqing | Heilongjiang | 163001 | China |
| The first affiliated hospital of Zhengzhou medical university | Zhengzhou | Henan | China |
| Zhongda Hospital Southeast University | Nanjing | Jiangsu | 210009 | China |
| The Second Affiliated Hospital of Nanchang University | Nanchang | Jiangxi | 330006 | China |
| The Second Hospital of Jilin University | Changchun | Jilin | 130000 | China |
| the second affiliated hospital of Dalian medical university | Dalian | Liaoning | China |
| Shenyang military district general hospital of the people's liberation army | Shenyang | Liaoning | China |
| The first affiliated hospital of military medical university | Xi’an | Shanxi | China |
| Third Military Medical University | Chongqing | Sichuan | China |
| The General Hospital of Tianjin Medical University | Tianjin | Tianjin Municipality | China |
| Tianjin Chest Hospital | Tianjin | Tianjin Municipality | China |
| The First Affiliated Hospital of Xinjiang Medical University | Ürümqi | Xinjiang | China |
| Lang X, Zhao B, Fang S, Li L, Li Z, Wu N, Zhang Y, Xing L, Li Y, Zhang Y. Higher Peripheral Thyroid Sensitivity Is Linked to a Lower Risk of Heart Failure After Acute Myocardial Infarction. J Clin Endocrinol Metab. 2023 Oct 18;108(11):2950-2960. doi: 10.1210/clinem/dgad240. |
| 36648054 | Derived | Zeng M, Zhao C, Bao X, Liu M, He L, Xu Y, Meng W, Qin Y, Weng Z, Yi B, Zhang D, Wang S, Luo X, Lv Y, Chen X, Sun Q, Feng X, Gao Z, Sun Y, Demuyakor A, Li J, Hu S, Guagliumi G, Mintz GS, Jia H, Yu B. Clinical Characteristics and Prognosis of MINOCA Caused by Atherosclerotic and Nonatherosclerotic Mechanisms Assessed by OCT. JACC Cardiovasc Imaging. 2023 Apr;16(4):521-532. doi: 10.1016/j.jcmg.2022.10.023. Epub 2022 Dec 14. |
| 35463775 | Derived | Li L, Zhang X, Wang Y, Yu X, Jia H, Hou J, Li C, Zhang W, Yang W, Liu B, Lu L, Tan N, Yu B, Li K. A Novel Risk Score to Predict In-Hospital Mortality in Patients With Acute Myocardial Infarction: Results From a Prospective Observational Cohort. Front Cardiovasc Med. 2022 Apr 7;9:840485. doi: 10.3389/fcvm.2022.840485. eCollection 2022. |