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This prospective and prospective cohort study aims to establish a long-term follow-up cohort of patients with acute myocardial infarction, and combine multi-omics studies, wearable devices, artificial intelligence technology, etc., to describe the clinical characteristics of patients with acute myocardial infarction and the changing trend of treatment strategies, and analyze the related influencing factors. Explore new biomarkers and indicators affecting recurrent cardiovascular events for accurate risk stratification and risk prediction; To evaluate the factors affecting lifestyle intervention, drug efficacy and safety, and their impact on outcome, and improve chronic disease management mode, in order to improve the quality of life and prognosis of patients.
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| Measure | Description | Time Frame |
|---|---|---|
| Major Adverse Cardiovascular Events | Composite end points of Cardiovascular death, nonfatal myocardial infarction, nonfatal ischemic stroke | 5 years |
| Measure | Description | Time Frame |
|---|---|---|
| Secondary Adverse Cardiovascular Events | All-cause death, non-cardiac death, myocardial infarction, hospitalization for coronary revascularization, hospitalization for heart failure, hospitalization for acute coronary syndrome, ischemic stroke, hemorrhagic stroke | 5 years |
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Inclusion Criteria:
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Patients hospitalized in the department of Cardiology or outpatient department of Peking University First Hospital will be enrolled if they are aged ≥18 years old, meet the inclusion criteria of acute myocardial infarction and need long-term follow-up according to the judgment of doctors after informed consent. There are about 7500 retrospectively enrolled patients, and it is expected to enroll 500 patients per year.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Jia Jia, MPH | Contact | 861083572283 | jiajia9985@163.com | |
| Bin Zhang, MD | Contact | 861083572645 | raisend0101@163.com |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Division of Cardiology, Peking University First Hospital | Recruiting | Beijing | Beijing Municipality | 100034 | China |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 24969506 | Background | Li J, Li X, Wang Q, Hu S, Wang Y, Masoudi FA, Spertus JA, Krumholz HM, Jiang L; China PEACE Collaborative Group. ST-segment elevation myocardial infarction in China from 2001 to 2011 (the China PEACE-Retrospective Acute Myocardial Infarction Study): a retrospective analysis of hospital data. Lancet. 2015 Jan 31;385(9966):441-51. doi: 10.1016/S0140-6736(14)60921-1. Epub 2014 Jun 23. | |
| 33095249 |
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| ID | Term |
|---|---|
| D003324 | Coronary Artery Disease |
| ID | Term |
|---|---|
| D003327 | Coronary Disease |
| D017202 | Myocardial Ischemia |
| D006331 | Heart Diseases |
| D002318 | Cardiovascular Diseases |
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| Background |
| Xu H, Yang Y, Wang C, Yang J, Li W, Zhang X, Ye Y, Dong Q, Fu R, Sun H, Yan X, Gao X, Wang Y, Jia X, Sun Y, Wu Y, Zhang J, Zhao W, Sabatine MS, Wiviott SD; China Acute Myocardial Infarction Registry Investigators. Association of Hospital-Level Differences in Care With Outcomes Among Patients With Acute ST-Segment Elevation Myocardial Infarction in China. JAMA Netw Open. 2020 Oct 1;3(10):e2021677. doi: 10.1001/jamanetworkopen.2020.21677. |
| 35293976 | Background | Hao Y, Zhao D, Liu J, Liu J, Yang N, Huo Y, Fonarow GC, Ge J, Morgan L, Ma C, Han Y, Smith SC Jr; CCC-ACS Investigators. Performance of Management Strategies With Class I Recommendations Among Patients Hospitalized With ST-Segment Elevation Myocardial Infarction in China. JAMA Cardiol. 2022 May 1;7(5):484-491. doi: 10.1001/jamacardio.2022.0117. |
| D001161 |
| Arteriosclerosis |
| D001157 | Arterial Occlusive Diseases |
| D014652 | Vascular Diseases |