Effect of Sleeve Gastrectomy on Pancreatic Exocrine Insufficiency.
Effect of Sleeve Gastrectomy on Pancreatic Exocrine Insufficiency.
Main proposed benefit of sleeve gastrectomy is loss of ghrelin secreting tissue. Some studies express that ghrelin augment pancreatic regeneration. Therefore we hypothesized that with sleeve gastrectomy it may result with pancreatic insufficiency.
Mechanism of weight loss differs in bariatric surgery according to type of surgery.
With sleeve gastrectomy which has restrictive mechanism, ghrelin excretion decreases, and this condition is attributed as an additional mechanism in weight loss.
Ghrelin effects pancreatic regeneration, and loss of ghrelin may result with pancreatic insufficiency. Therefore we aimed to deteremine this association.
Inclusion Criteria:
Patients underwent bariatric surgery (Sleeve gastrectomy) after concordonce with NIH criteria
Exclusion Criteria:
Additional operations to sleeve gastrectomy like duodenal switch. Other bariatric operations.
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