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The study compares early palliative care consultation to standard of care in the medical intensive care unit (ICU). The study will assess if the intervention leads to an increased proportion of clearly delineated goals of care and examine if this intervention leads to decreased healthcare resource utilization such as length of stay, duration of intensive treatments including mechanical ventilation, and hospital re-admissions.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Standard of Care | No Intervention | ||
| Early Palliative Care Consultation | Other |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Palliative Care | Other | Palliative Care Consultation within 24 to 48 hours after admission |
|
| Measure | Description | Time Frame |
|---|---|---|
| Change in code status to do-not-resuscitate/do-not-intubate | As determined by code status orders in the electronic medical record | Through patient admission until discharge, charts reviewed an average of one month after discharge |
| Measure | Description | Time Frame |
|---|---|---|
| Number of participants with Cardiopulmonary Resuscitation (CPR) performed | Through study completion, an average of 6 months | |
| Mechanical Ventilation usage and duration | After date of discharge, charts reviewed an average of one month after discharge |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Barnes Jewish Hospital | St Louis | Missouri | 63110 | United States |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 28306372 | Background | Adelson K, Paris J, Horton JR, Hernandez-Tellez L, Ricks D, Morrison RS, Smith CB. Standardized Criteria for Palliative Care Consultation on a Solid Tumor Oncology Service Reduces Downstream Health Care Use. J Oncol Pract. 2017 May;13(5):e431-e440. doi: 10.1200/JOP.2016.016808. Epub 2017 Mar 17. | |
| 24517300 | Background |
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| ID | Term |
|---|---|
| D010166 | Palliative Care |
| ID | Term |
|---|---|
| D005791 | Patient Care |
| D013812 | Therapeutics |
| D006296 | Health Services |
| D005159 | Health Care Facilities Workforce and Services |
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| Hospital Length of Stay | After date of discharge, charts reviewed an average of one month after discharge |
| ICU Length of Stay | After date of discharge, charts reviewed an average of one month after discharge |
| In-hospital mortality | Excluding patients transitioned to hospice prior to death | After date of discharge, charts reviewed an average of one month after discharge |
| 30-day mortality | Including all patients, including those on hospice | One to two months after patient discharge, verified at study completion |
| Hospice transition or discharge | Through patient admission until discharge, charts reviewed an average of one month after discharge |
| Post-discharge ER visits and/or readmissions | Determined by review of the BJC healthcare system electronic medical record | One to two months after patient discharge, verified at study completion |
| Total hospital operating cost | Through study completion, an average of 6 months |
| Vasopressor usage and duration | After date of discharge, charts reviewed an average of one month after discharge |
| Antibiotic usage and duration | After date of discharge, charts reviewed an average of one month after discharge |
| Number of participants treated with hemodialysis | Through study completion, an average of six months |
| Number of participants with tracheostomy performed during hospital stay | Through study completion, an average of six months |
| Aslakson R, Cheng J, Vollenweider D, Galusca D, Smith TJ, Pronovost PJ. Evidence-based palliative care in the intensive care unit: a systematic review of interventions. J Palliat Med. 2014 Feb;17(2):219-35. doi: 10.1089/jpm.2013.0409. |
| 24603677 | Background | Hsu-Kim C, Friedman T, Gracely E, Gasperino J. Integrating Palliative Care into Critical Care: A Quality Improvement Study. J Intensive Care Med. 2015 Sep;30(6):358-64. doi: 10.1177/0885066614523923. Epub 2014 Mar 5. |
| 25574794 | Background | Khandelwal N, Kross EK, Engelberg RA, Coe NB, Long AC, Curtis JR. Estimating the effect of palliative care interventions and advance care planning on ICU utilization: a systematic review. Crit Care Med. 2015 May;43(5):1102-11. doi: 10.1097/CCM.0000000000000852. |
| 27582396 | Background | Kyeremanteng K, Gagnon LP, Thavorn K, Heyland D, D'Egidio G. The Impact of Palliative Care Consultation in the ICU on Length of Stay: A Systematic Review and Cost Evaluation. J Intensive Care Med. 2018 Jun;33(6):346-353. doi: 10.1177/0885066616664329. Epub 2016 Aug 31. |
| 22202706 | Background | Penrod JD, Pronovost PJ, Livote EE, Puntillo KA, Walker AS, Wallenstein S, Mercado AF, Swoboda SM, Ilaoa D, Thompson DA, Nelson JE. Meeting standards of high-quality intensive care unit palliative care: clinical performance and predictors. Crit Care Med. 2012 Apr;40(4):1105-12. doi: 10.1097/CCM.0b013e3182374a50. |
| 27644048 | Background | Mun E, Ceria-Ulep C, Umbarger L, Nakatsuka C. Trend of Decreased Length of Stay in the Intensive Care Unit (ICU) and in the Hospital with Palliative Care Integration into the ICU. Perm J. 2016 Fall;20(4):16-036. doi: 10.7812/TPP/16-036. Epub 2016 Aug 31. |
| 26556622 | Background | Braus N, Campbell TC, Kwekkeboom KL, Ferguson S, Harvey C, Krupp AE, Lohmeier T, Repplinger MD, Westergaard RP, Jacobs EA, Roberts KF, Ehlenbach WJ. Prospective study of a proactive palliative care rounding intervention in a medical ICU. Intensive Care Med. 2016 Jan;42(1):54-62. doi: 10.1007/s00134-015-4098-1. Epub 2015 Nov 10. |
| 31609772 | Derived | Ma J, Chi S, Buettner B, Pollard K, Muir M, Kolekar C, Al-Hammadi N, Chen L, Kollef M, Dans M. Early Palliative Care Consultation in the Medical ICU: A Cluster Randomized Crossover Trial. Crit Care Med. 2019 Dec;47(12):1707-1715. doi: 10.1097/CCM.0000000000004016. |